HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MTCH2 (Q9Y6C9)
Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein)
Gene: MTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 303
+	Hs
		497760 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2513_HUMAN (100-302): 1.38e-37: 143: 16.91
+	Hs
		496184 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT3_HUMAN (113-299): 3.27e-29: 114: 14.00
+	Hs
		397240 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT2_HUMAN (113-299): 1.34e-28: 113: 13.50
+	Hs
		496183 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT1_HUMAN (113-299): 2e-28: 112: 13.78
+	Hs
		274476 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2512_HUMAN (4-115): 2e-18: 87.3: 14.29
+	Rn
		581991 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT1_RAT (113-299): 4.95e-29: 114: 14.80
+	Rn
		94213 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT1_RAT (113-299): 4.95e-29: 114: 14.80
+	Rn
		581994 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT2_RAT (113-299): 8.57e-29: 113: 13.50
+	Rn
		94216 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT2_RAT (113-299): 8.57e-29: 113: 13.50
+	Mm
		497947 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT1_MOUSE (113-299): 4.8e-29: 114: 14.80
+	Mm
		497951 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT2_MOUSE (113-299): 6.68e-29: 113: 13.50
+	Mm
		498076 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		S2512_MOUSE (4-115): 1.65e-18: 87.6: 14.29