HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 718
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		497209 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR87_HUMAN (56-522): 1.26e-12: 73.8: 19.96
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (421-698): 3.46e-12: 72.4: 11.51
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (393-713): 4.3e-12: 72: 11.53
+	Hs
		496228 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		497371 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MY18A_HUMAN (44-521): 2.6e-09: 63: 15.87
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (393-713): 2.23e-12: 73.1: 11.53
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (393-713): 2.23e-12: 73.1: 11.53
+	Hs
		148818 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		149481 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98