HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: STK24 (Q9Y6E0)
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
Gene: STK24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 443
+	Hs
		496408 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT2_HUMAN (1-357): 5.34e-136: 401: 23.84
+	Hs
		496407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		496307 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KAPCB_HUMAN (14-325): 9.95e-130: 380: 24.06
+	Hs
		496248 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KAPCA_HUMAN (14-340): 1.26e-129: 379: 23.88
+	Hs
		277594 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PAK3_HUMAN (30-312): 1.02e-117: 356: 44.56
+	Hs
		496951 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PAK2_HUMAN (30-309): 3.54e-118: 356: 43.97
+	Hs
		497766 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70
+	Hs
		152597 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		AKT1_HUMAN (1-357): 1.55e-134: 397: 24.32
+	Hs
		503264 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		KAPCB_HUMAN (14-325): 9.95e-130: 380: 24.06
+	Hs
		503261 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		KAPCA_HUMAN (14-340): 1.26e-129: 379: 23.88
+	Hs
		1356429 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70