Protein: HYPD
Hydrogenase maturation factor HypD (Hydrogenase isoenzymes formation protein HypD)

Gene: HYPD
Organism: Escherichia coli K-12
Interactions: 19
UniProt ID: P24192

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0016887 - ATP hydrolysis activity
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0051604 - protein maturation
GO:0065003 - protein-containing complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497911

HYBG
Hydrogenase maturation factor HybG

2

3

Small-scale

0.822

High

497903

HYPC
Hydrogenase maturation factor HypC

2

2

Small-scale

0.735

High

664146

HYPE
Carbamoyl dehydratase HypE

4

2

Small-scale

0.683

High

489705

CH60
Chaperonin GroEL

2

0

High-throughput

0.602

High

506274

EFTU1
Elongation factor Tu 1

2

1

High-throughput

0.558

High

492296

RECA
Protein RecA

1

0

High-throughput

0.479

High

473310

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.458

High

664147

CLPB
Chaperone protein ClpB

1

0

High-throughput

0.458

High

506336

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.457

High

499029

MBHM
Hydrogenase-2 large chain

2

0

Small-scale

0.298

High

664148

ALAC
Glutamate-pyruvate aminotransferase AlaC

1

0

High-throughput

0.279

Low

490159

CH10
Co-chaperonin GroES

1

0

High-throughput

0.261

Low

492955

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.261

Low

450038

OMPC
Outer membrane porin C

1

0

High-throughput

0.249

Low

489355

ISCS
Cysteine desulfurase IscS

1

0

High-throughput

0.249

Low

490522

EFG
Elongation factor G

1

0

High-throughput

0.249

Low

497351

MREB
Cell shape-determining protein MreB

1

0

High-throughput

0.249

Low

498585

DPS
DNA protection during starvation protein

1

0

High-throughput

0.249

Low

505909

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025