HitPredict

Interactor 1: HNS (P0ACF8)
DNA-binding protein H-NS (Heat-stable nucleoid-structuring protein) (Histone-like protein HLP-II) (Protein B1) (Protein H1)
Gene: HNS

Interactor 2: CNU (P64467)
OriC-binding nucleoid-associated protein (H-NS/StpA-binding protein 2) (Transcription modulator YdgT)
Gene: CNU

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	19402753, 15690043, 21600204
Identification Methods	tandem affinity purification, nuclear magnetic resonance, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	HHA~Histone_HNS_N
Common GO terms	GO:0036386 - bacterial nucleoid DNA packaging GO:0036411 - H-NS-Cnu complex GO:0045892 - negative regulation of DNA-templated transcription GO:1900232 - negative regulation of single-species biofilm formation on inanimate substrate
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 137 Ec			1 71
+	Ec
		499034 HNS_ECOLI (1-137): 6.36e-56: 172: 100.00		HHA_ECOLI (1-71): 6.85e-24: 86.6: 38.03