Protein: PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2 (EC 3.1.3.16) (Calcineurin A2) (Calmodulin-binding protein 2)

Gene: PP2B2, CMP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P14747

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005955 - calcineurin complex
GO:0006873 - intracellular monoatomic ion homeostasis
GO:0017018 - myosin phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540208

CANB
Calcineurin subunit B

6

20

High-throughput

0.942

High

420209

CALM
Calmodulin

6

17

Small-scale

0.847

High

540207

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

2

14

Small-scale

0.755

High

540220

RCN1
Calcipressin-like protein

2

1

Small-scale

0.595

High

365703

HSP82
ATP-dependent molecular chaperone HSP82

2

5

Small-scale

0.584

High

540238

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

540241

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

2

5

Small-scale

0.574

High

540262

RUVB2
RuvB-like protein 2

2

6

High-throughput

0.565

High

490204

HSP71
Heat shock protein SSA1

2

14

High-throughput

0.552

High

540233

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.552

High

526178

KIN2
Serine/threonine-protein kinase KIN2

1

8

High-throughput

0.536

High

540219

EF1G2
Elongation factor 1-gamma 2

1

3

High-throughput

0.536

High

540225

KSP1
Serine/threonine-protein kinase KSP1

1

12

High-throughput

0.536

High

540253

RGC1
Regulator of the glycerol channel 1

1

5

High-throughput

0.536

High

540264

HPH1
Protein HPH1

2

1

Small-scale

0.535

High

540204

GCN2
eIF-2-alpha kinase GCN2

1

9

High-throughput

0.515

High

524131

CAF20
Cap-associated protein CAF20

1

2

Small-scale

0.501

High

540213

MLF3
Protein MLF3

1

1

Small-scale

0.501

High

540214

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

6

Small-scale

0.501

High

540216

ELM1
Serine/threonine-protein kinase ELM1

1

2

Small-scale

0.501

High

540221

ALY1
Arrestin-related trafficking adapter 6

1

4

Small-scale

0.501

High

540226

KIC1
Serine/threonine-protein kinase KIC1

1

11

Small-scale

0.501

High

540235

RTS2
Zinc finger protein RTS2

1

1

Small-scale

0.501

High

540237

STB1
Protein STB1

1

1

Small-scale

0.501

High

540242

CRZ1
Transcriptional regulator CRZ1

1

3

Small-scale

0.501

High

540243

ROD1
Protein ROD1

1

4

Small-scale

0.501

High

540247

TDA1
Serine/threonine-protein kinase TDA1

1

10

Small-scale

0.501

High

540248

LIC4
Protein ATC1/LIC4

1

1

Small-scale

0.501

High

540254

SKG3
Protein SKG3

1

1

Small-scale

0.501

High

540255

RGA2
Rho-type GTPase-activating protein 2

1

5

Small-scale

0.501

High

540257

YO352
Uncharacterized protein YOR352W

1

1

Small-scale

0.501

High

540259

RCN2
Regulator of calcineurin 2

1

1

Small-scale

0.501

High

540263

YP247
WD repeat-containing protein YPL247C

1

13

Small-scale

0.501

High

404293

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

1

High-throughput

0.500

High

424319

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.500

High

540205

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.500

High

540239

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

4

High-throughput

0.489

High

540234

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

5

Small-scale

0.481

High

381415

GAL1
Galactokinase

1

0

High-throughput

0.479

High

498422

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

540236

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.479

High

540203

HSC82
ATP-dependent molecular chaperone HSC82

1

5

Small-scale

0.479

High

540209

BPH1
Beige protein homolog 1

1

7

High-throughput

0.479

High

540212

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

540227

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

540261

INP53
Polyphosphatidylinositol phosphatase INP53

1

3

Small-scale

0.479

High

540217

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

498775

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.457

High

540215

SRP40
Suppressor protein SRP40

1

10

Small-scale

0.457

High

540222

YB75
Uncharacterized protein YBR225W

1

2

Small-scale

0.457

High

540223

UBX7
UBX domain-containing protein 7

1

5

Small-scale

0.457

High

540228

SFB3
SED5-binding protein 3

1

1

Small-scale

0.457

High

540229

SPT8
Transcription factor SPT8

1

1

Small-scale

0.457

High

540230

UME6
Transcriptional regulatory protein UME6

1

1

Small-scale

0.457

High

540231

NUP60
Nucleoporin NUP60

1

1

Small-scale

0.457

High

540240

ZRG17
Protein ZRG17

1

1

Small-scale

0.457

High

540245

JIP4
Uncharacterized protein JIP4

1

3

Small-scale

0.457

High

540246

DIG2
Down-regulator of invasive growth 2

1

1

Small-scale

0.457

High

540256

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.457

High

341901

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

378268

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.457

High

540206

HSP60
Heat shock protein 60, mitochondrial

1

3

High-throughput

0.457

High

412510

CDC7
Cell division control protein 7

1

20

Small-scale

0.445

High

493091

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

510120

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

540232

FIR1
Factor interacting with REF2

1

2

Small-scale

0.439

High

540258

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

540249

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

540218

SPT7
Transcriptional activator SPT7

1

9

High-throughput

0.407

High

540244

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.407

High

540260

HFI1
Transcriptional coactivator HFI1/ADA1

1

1

High-throughput

0.407

High

540211

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

0

High-throughput

0.279

Low

540224

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.279

Low

540252

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.279

Low

540210

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.261

Low

540250

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

540251

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024