HitPredict

Interactor 1: EVGA (P0ACZ4)
DNA-binding transcriptional activator EvgA
Gene: EVGA

Interactor 2: NTRC (P0AFB8)
DNA-binding transcriptional regulator NtrC (Nitrogen regulation protein NR(I)) (Nitrogen regulator I) (NRI)
Gene: glnG

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.764

Property	Details
Experiments	24561554
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, pull down, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	GerE~Response_reg, Response_reg~Response_reg, Response_reg~Sigma54_activat
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 204 Ec			1 469
+	Mx
		1167367 Q1D1K9_MYXXD (2-202): 2.11e-49: 161: 16.51		Q1D0A2_MYXXD (2-468): 2.05e-152: 443: 36.03
+	Mx
		1167337 Q1CZP3_MYXXD (2-203): 1.37e-46: 154: 16.90		Q1D0A2_MYXXD (2-468): 2.05e-152: 443: 36.03
+	Mx
		1167348 Q1D8M8_MYXXD (3-200): 5.64e-47: 156: 16.74		Q1D033_MYXXD (5-468): 8.18e-151: 439: 42.55
+	Mx
		1167231 Q1D8M8_MYXXD (3-200): 5.64e-47: 156: 16.74		Q1CWG7_MYXXD (2-469): 8.95e-148: 432: 38.46
+	Ec
		499508 EVGA_ECOLI (1-204): 7.77e-47: 154: 100.00		FHLA_ECOLI (57-469): 1.19e-116: 359: 35.10
+	Ss
		1001178 P73864_SYNY3 (1-203): 1.07e-48: 159: 18.98		P72948_SYNY3 (4-249): 7.87e-51: 174: 19.68
+	Ec
		500873 PHOB_ECOLI (2-202): 1.25e-52: 170: 14.09		PHOB_ECOLI (1-218): 3.32e-45: 159: 20.09
+	Ec
		497560 PHOB_ECOLI (2-202): 1.25e-52: 170: 14.09		OMPR_ECOLI (2-188): 9.01e-40: 145: 22.46
+	Mx
		1167388 Q1D8M8_MYXXD (3-200): 5.64e-47: 156: 16.74		Q1D1K9_MYXXD (5-216): 9.94e-45: 157: 26.61
+	Mx
		1167441 Q1D4T4_MYXXD (2-202): 6.47e-50: 163: 14.73		Q1D4T4_MYXXD (2-233): 4.43e-42: 150: 20.34
+	Ec
		1003819 HPRR_ECOLI (1-202): 1.3e-47: 157: 17.05		HPRR_ECOLI (4-204): 6.73e-43: 152: 18.54
+	Ec
		999444 BAER_ECOLI (2-204): 1.04e-47: 158: 15.39		BAER_ECOLI (4-256): 3.76e-42: 151: 19.76
+	Bt
		1295809 Q89YR8_BACTN (2-203): 7.71e-45: 160: 16.75		Q89YR8_BACTN (2-164): 1.17e-37: 148: 28.49
+	Ec
		499509 EVGA_ECOLI (1-204): 7.77e-47: 154: 100.00		EVGS_ECOLI (2-200): 3.93e-39: 153: 18.50
+	Ec
		499519 HPRR_ECOLI (1-202): 1.3e-47: 157: 17.05		CUSR_ECOLI (4-216): 9.63e-42: 150: 17.73
+	Ec
		497558 OMPR_ECOLI (2-199): 1.25e-46: 155: 13.58		CPXR_ECOLI (5-237): 1.11e-41: 150: 20.25
+	Ec
		497556 OMPR_ECOLI (2-199): 1.25e-46: 155: 13.58		OMPR_ECOLI (2-188): 9.01e-40: 145: 22.46
+	Ec
		663237 PHOP_ECOLI (1-202): 1.03e-46: 154: 14.68		PHOP_ECOLI (5-181): 5.87e-39: 142: 22.03
+	Af
		1261032 Q7CXM1_AGRFC (2-204): 2.58e-46: 154: 16.06		Q7CXM1_AGRFC (4-167): 7.59e-38: 139: 26.83