Interactor 1: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Interactor 2: RPAB1 (P20434)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (ABC27) (DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide)
Gene: RPB5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 10393904, 11805837, 11805826, 16554755, 17179178, 21954159, 14759368, 24307683, 11918799, 16429126, 37968396, 21048197
Identification Methods two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb5_C, RNA_pol_Rpb1_1~RNA_pol_Rpb5_N, RNA_pol_Rpb1_5~RNA_pol_Rpb5_C, RNA_pol_Rpb1_5~RNA_pol_Rpb5_N
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1664
Sc

1 215
+ Hs
+ Bt
+ Hs
+ At
+ Sp
+ Sc
+ Hv
+ Sc
+ Hs
+ At
+ At
+ At
+ At
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024