Interactor 1: IAPP (P10997)
Islet amyloid polypeptide (Amylin) (Diabetes-associated peptide) (DAP) (Insulinoma amyloid peptide)
Gene: IAPP

Interactor 2: IAPP (P10997)
Islet amyloid polypeptide (Amylin) (Diabetes-associated peptide) (DAP) (Insulinoma amyloid peptide)
Gene: IAPP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.964

The method score is based on:

Property Details
Experiments 17640888, 18408164, 26840340, 32541895, 21130765, 24042052, 24561193
Identification Methods transmission electron microscopy, x-ray fiber diffraction, classical fluorescence spectroscopy, 3D electron microscopy, aggregation assay, molecular sieving, fluorescence technology, dynamic light scattering, atomic force microscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Calc_CGRP_IAPP~Calc_CGRP_IAPP
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
and 18 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 89
Hs

1 89
+ Ss

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024