Protein: MRM3
rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1)

Gene: MRM3
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q9HC36

Gene Ontology (top 5):
GO:0000451 - rRNA 2'-O-methylation
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1438587

MRM3
rRNA methyltransferase 3, mitochondrial

2

1

High-throughput

0.783

High

1234534

MRM1
rRNA methyltransferase 1, mitochondrial

2

2

High-throughput

0.754

High

282092

MPPB
Mitochondrial-processing peptidase subunit beta

4

1

High-throughput

0.694

High

856390

IF2M
Translation initiation factor IF-2, mitochondrial

3

1

High-throughput

0.667

High

1083760

MPPA
Mitochondrial-processing peptidase subunit alpha

3

1

High-throughput

0.667

High

1094126

RM28
Large ribosomal subunit protein bL28m

3

0

High-throughput

0.638

High

1418250

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.638

High

1438588

RM47
Large ribosomal subunit protein uL29m

3

0

High-throughput

0.638

High

1438589

RT30
Large ribosomal subunit protein mL65

3

0

High-throughput

0.638

High

1438595

RM39
Large ribosomal subunit protein mL39

3

0

High-throughput

0.638

High

1087562

GRSF1
G-rich sequence factor 1

3

0

Small-scale

0.613

High

278756

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.602

High

662807

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

2

0

High-throughput

0.602

High

1328073

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.602

High

1328298

RM50
Large ribosomal subunit protein mL50

2

0

High-throughput

0.602

High

1389010

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

2

0

High-throughput

0.602

High

1438614

RM42
Large ribosomal subunit protein mL42

2

0

High-throughput

0.602

High

1123436

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

1415678

TR61B
tRNA

2

0

High-throughput

0.585

High

1438592

DDX28
Probable ATP-dependent RNA helicase DDX28

2

0

High-throughput

0.585

High

279923

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1162565

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1058289

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

Small-scale

0.547

High

396982

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

287147

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

0

High-throughput

0.513

High

428997

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

693993

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

970115

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

978738

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

1016624

SRSF3
Serine/arginine-rich splicing factor 3

1

0

High-throughput

0.513

High

1152254

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1213347

RM02
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.513

High

1272325

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

1

0

High-throughput

0.513

High

1281343

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.513

High

1349553

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.513

High

1351049

DDX54
ATP-dependent RNA helicase DDX54

1

0

High-throughput

0.513

High

1360486

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1389283

RM53
Large ribosomal subunit protein mL53

1

0

High-throughput

0.513

High

1418136

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.513

High

1430509

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.513

High

1438606

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

298547

SPF30
Survival of motor neuron-related-splicing factor 30

1

0

High-throughput

0.493

High

785861

8ODP
Oxidized purine nucleoside triphosphate hydrolase

1

0

High-throughput

0.493

High

910694

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.493

High

1008592

NTH
Endonuclease III-like protein 1

1

0

High-throughput

0.493

High

1151661

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.493

High

1438604

PUF60
Poly(U)-binding-splicing factor PUF60

1

0

High-throughput

0.493

High

1112722

CUL1
Cullin-1

1

1

High-throughput

0.489

High

1199463

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

1

High-throughput

0.489

High

1273908

BHA15
Class A basic helix-loop-helix protein 15

1

1

High-throughput

0.489

High

1438611

NGN3
Neurogenin-3

1

1

High-throughput

0.489

High

1438609

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

287384

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

401516

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

521442

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.479

High

1138654

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1215841

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1273000

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.479

High

1367324

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1381731

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.479

High

1401627

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1420361

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

1432626

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1438021

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1438596

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

2

High-throughput

0.479

High

1438601

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1112993

CUL2
Cullin-2

1

1

High-throughput

0.470

High

66299

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

135833

RTCA
RNA 3'-terminal phosphate cyclase

1

0

High-throughput

0.458

High

183743

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

231271

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.458

High

351003

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

471260

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

473099

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

519234

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532982

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

828969

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841961

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852038

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882899

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

1024195

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1024855

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1048707

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1090551

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1092246

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1117849

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1142673

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1161684

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1207150

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1271563

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1290740

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1386025

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

1387762

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

1388279

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388416

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1403436

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1407885

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1412442

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1413023

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1416550

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1418890

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1428736

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1431967

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1432314

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1433726

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1435791

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1436092

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1438590

NGRN
Neugrin

1

0

High-throughput

0.458

High

1438594

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1438597

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1438598

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1438608

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1437330

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

1438607

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.445

High

373196

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406667

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

1438605

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

288780

NPM3
Nucleoplasmin-3

1

0

High-throughput

0.426

High

686446

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.426

High

810395

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

967564

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.426

High

1006730

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.426

High

1239945

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1346936

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.426

High

1327335

ZN276
Zinc finger protein 276

1

1

High-throughput

0.407

High

1413885

ZN692
Zinc finger protein 692

1

1

High-throughput

0.407

High

1116591

FHL3
Four and a half LIM domains protein 3

3

0

High-throughput

0.352

High

913811

ZN131
Zinc finger protein 131

3

0

High-throughput

0.347

High

1438591

LUC7L
Putative RNA-binding protein Luc7-like 1

3

0

High-throughput

0.347

High

1385100

PTER
N-acetyltaurine hydrolase

2

0

High-throughput

0.328

High

1403657

UHRF1
E3 ubiquitin-protein ligase UHRF1

2

0

High-throughput

0.328

High

1438599

KLH42
Kelch-like protein 42

2

0

High-throughput

0.328

High

327457

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.316

High

378186

TNFA
Tumor necrosis factor

2

0

High-throughput

0.316

High

719086

MIP
Lens fiber major intrinsic protein

2

0

High-throughput

0.316

High

1050873

DCE2
Glutamate decarboxylase 2

2

0

High-throughput

0.316

High

1083155

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.316

High

1122477

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.316

High

1328204

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

1358619

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.316

High

1358715

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

2

0

High-throughput

0.316

High

1438593

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.316

High

1438613

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.316

High

423216

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.314

High

1417957

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.282

High

288203

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.279

Low

338547

SC24B
Protein transport protein Sec24B

1

0

High-throughput

0.279

Low

723964

LCN1
Lipocalin-1

1

0

High-throughput

0.279

Low

867434

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

1104330

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.279

Low

1291223

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.279

Low

1398080

ZN512
Zinc finger protein 512

1

0

High-throughput

0.279

Low

186037

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

248098

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

316031

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

317680

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.249

Low

320065

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

363884

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

607654

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

0

High-throughput

0.249

Low

659597

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.249

Low

941569

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

1067731

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.249

Low

1087692

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.249

Low

1107229

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1217428

OBSCN
Obscurin

1

0

High-throughput

0.249

Low

1228603

SPT2
Protein SPT2 homolog

1

0

High-throughput

0.249

Low

1255620

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1257135

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.249

Low

1368626

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

1370951

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

1393714

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1428631

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1433941

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1438600

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

1438602

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1438603

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.249

Low

1438610

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.249

Low

1438612

MAFB
Transcription factor MafB

1

0

High-throughput

0.249

Low

584149

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.232

Low

1037383

H11
Histone H1.1

1

0

High-throughput

0.232

Low

1290432

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

0

High-throughput

0.232

Low

1315253

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.232

Low

1430428

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.232

Low

1435551

GREM2
Gremlin-2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025