HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: LAMC1 (P11047)
Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma)
Gene: LAMC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33957083, 34349018
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 1609
+	Hs
		502805 HSP7C_HUMAN (26-637): 0: 916: 66.02		LAMC1_HUMAN (1-1609): 0: 1092: 100.00
+	Hs
		433114 BIP_HUMAN (19-654): 0: 914: 100.00		LAMB1_HUMAN (21-1561): 0: 668: 20.81
+	Hs
		502002 BIP_HUMAN (19-654): 0: 914: 100.00		NOTC2_HUMAN (267-880): 2.73e-47: 189: 12.77
+	Hs
		501701 BIP_HUMAN (19-654): 0: 914: 100.00		LAMA1_HUMAN (305-497): 1.04e-27: 125: 26.70
+	Hs
		501880 BIP_HUMAN (19-654): 0: 914: 100.00		LAMB2_HUMAN (1194-1543): 3.11e-10: 67.6: 12.57