HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33957083, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 602
+	Hs
		502711 BIP_HUMAN (19-654): 0: 914: 100.00		MTCL1_HUMAN (14-552): 1.35e-29: 127: 14.00
+	Hs
		504591 HSP7C_HUMAN (26-637): 0: 916: 66.02		CFA57_HUMAN (129-562): 6.6e-27: 118: 15.65
+	Hs
		502023 BIP_HUMAN (19-654): 0: 914: 100.00		CGNL1_HUMAN (34-599): 7e-24: 109: 12.13
+	Hs
		148449 HS71L_HUMAN (24-647): 0: 922: 63.16		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		501756 BIP_HUMAN (19-654): 0: 914: 100.00		MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72
+	Hs
		148327 HSP7C_HUMAN (26-637): 0: 916: 66.02		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		148367 HSP76_HUMAN (25-635): 0: 915: 62.54		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		148326 BIP_HUMAN (19-654): 0: 914: 100.00		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		148576 HSP72_HUMAN (25-636): 0: 905: 64.51		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		504210 HSP7C_HUMAN (26-637): 0: 916: 66.02		FKB15_HUMAN (281-582): 9.2e-12: 70.4: 11.92
+	Hs
		502805 HSP7C_HUMAN (26-637): 0: 916: 66.02		LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71
+	Hs
		501606 BIP_HUMAN (19-654): 0: 914: 100.00		LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71
+	Hs
		501755 BIP_HUMAN (19-654): 0: 914: 100.00		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		502274 BIP_HUMAN (19-654): 0: 914: 100.00		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		871601 HSP72_HUMAN (25-636): 0: 905: 64.51		FKB15_HUMAN (281-582): 9.2e-12: 70.4: 11.92