HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Hs			1 125
+	Hs
		714067 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		714074 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		504720 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		564178 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		713934 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305992 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		483769 HS71A_HUMAN (26-635): 0: 911: 64.11		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		504756 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		564184 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		502557 BIP_HUMAN (19-654): 0: 914: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		714070 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		503785 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		564050 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305925 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		501893 BIP_HUMAN (19-654): 0: 914: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305951 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		305924 BIP_HUMAN (19-654): 0: 914: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		504734 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		564180 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		502539 BIP_HUMAN (19-654): 0: 914: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46