Protein: NAT10
RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (Killer toxin-resistance protein 33) (Ribosomal RNA cytidine acetyltransferase 1)

Gene: NAT10, KRE33
Organism: Saccharomyces cerevisiae S288C
Interactions: 216
UniProt ID: P53914

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002101 - tRNA wobble cytosine modification
GO:0005524 - ATP binding
GO:0005730 - nucleolus
GO:0016556 - mRNA modification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

512578

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.754

High

924641

NOC4
Nucleolar complex protein 4

9

2

Small-scale

0.750

High

678438

PWP2
Periodic tryptophan protein 2

8

2

Small-scale

0.748

High

817608

UTP7
U3 small nucleolar RNA-associated protein 7

6

1

High-throughput

0.735

High

677513

KRR1
KRR1 small subunit processome component

6

1

High-throughput

0.732

High

798283

ENP1
Essential nuclear protein 1

11

0

Small-scale

0.722

High

924623

DHR1
Probable ATP-dependent RNA helicase DHR1

7

0

Small-scale

0.705

High

924640

RRP9
Ribosomal RNA-processing protein 9

4

3

High-throughput

0.694

High

924671

NOP58
Nucleolar protein 58

4

4

High-throughput

0.694

High

871037

NOL10
Ribosome biogenesis protein ENP2

4

1

High-throughput

0.691

High

924627

RRP5
rRNA biogenesis protein RRP5

4

1

Small-scale

0.686

High

918798

UTP22
U3 small nucleolar RNA-associated protein 22

5

0

High-throughput

0.686

High

823370

UTP18
U3 small nucleolar RNA-associated protein 18

4

0

High-throughput

0.666

High

806555

UTP9
U3 small nucleolar RNA-associated protein 9

4

0

High-throughput

0.664

High

924652

UTP16
U3 small nucleolar RNA-associated protein 16

4

0

High-throughput

0.664

High

924603

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.663

High

791085

NOP4
Nucleolar protein 4

3

1

High-throughput

0.662

High

924626

UTP14
U3 small nucleolar RNA-associated protein 14

4

0

High-throughput

0.659

High

924611

UTP6
U3 small nucleolar RNA-associated protein 6

4

0

High-throughput

0.657

High

754316

DCA13
Protein SOF1

3

3

High-throughput

0.656

High

924642

BFR2
Protein BFR2

3

1

High-throughput

0.650

High

924606

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

3

1

High-throughput

0.640

High

924633

UTP21
U3 small nucleolar RNA-associated protein 21

3

3

Small-scale

0.640

High

924643

UTP4
U3 small nucleolar RNA-associated protein 4

3

3

Small-scale

0.640

High

924656

BMS1
Ribosome biogenesis protein BMS1

3

1

High-throughput

0.640

High

924672

RRP12
Ribosomal RNA-processing protein 12

3

1

Small-scale

0.640

High

924674

NOP14
Nucleolar complex protein 14

3

0

High-throughput

0.638

High

758322

HSL1
Probable serine/threonine-protein kinase HSL1

2

1

High-throughput

0.621

High

924638

ESF1
Pre-rRNA-processing protein ESF1

2

1

High-throughput

0.614

High

673213

RRP7
Ribosomal RNA-processing protein 7

3

0

High-throughput

0.613

High

763605

UTP20
U3 small nucleolar RNA-associated protein 20

3

0

High-throughput

0.613

High

844566

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

919153

UTP8
U3 small nucleolar RNA-associated protein 8

3

0

Small-scale

0.613

High

149891

RS9A
Small ribosomal subunit protein uS4A

2

2

High-throughput

0.611

High

435270

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.611

High

803904

CIC1
Proteasome-interacting protein CIC1

2

1

High-throughput

0.611

High

918419

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.611

High

382260

H4
Histone H4

3

1

High-throughput

0.604

High

545833

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.601

High

632714

DBP4
ATP-dependent RNA helicase HCA4

2

6

High-throughput

0.601

High

923238

ESF2
Pre-rRNA-processing protein ESF2

2

1

High-throughput

0.601

High

518357

IF4A
ATP-dependent RNA helicase eIF4A

2

0

High-throughput

0.595

High

518100

SSBP1
Single-stranded nucleic acid-binding protein

2

0

High-throughput

0.592

High

924635

SGD1
Suppressor of glycerol defect protein 1

2

0

High-throughput

0.588

High

436095

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.585

High

689590

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.585

High

826200

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

747035

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

2

High-throughput

0.584

High

782087

RL1D1
Ribosome biogenesis protein UTP30

2

1

High-throughput

0.584

High

818326

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

1

High-throughput

0.584

High

924614

UTP17
NET1-associated nuclear protein 1

2

4

High-throughput

0.584

High

924622

UTP5
U3 small nucleolar RNA-associated protein 5

2

2

High-throughput

0.584

High

924624

UTP15
U3 small nucleolar RNA-associated protein 15

2

2

High-throughput

0.584

High

924632

UTP13
U3 small nucleolar RNA-associated protein 13

2

5

High-throughput

0.584

High

924661

RRP6
Exosome complex exonuclease RRP6

2

1

High-throughput

0.584

High

924664

UTP12
U3 small nucleolar RNA-associated protein 12

2

3

High-throughput

0.584

High

747508

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.571

High

512131

RS4A
Small ribosomal subunit protein eS4A

2

0

High-throughput

0.559

High

672929

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

865151

MPP10
U3 small nucleolar RNA-associated protein MPP10

2

0

High-throughput

0.559

High

924637

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

0

High-throughput

0.559

High

924647

RCL1
rRNA processing protein RCL1

2

0

High-throughput

0.559

High

924675

PNO1
Pre-rRNA-processing protein PNO1

2

0

High-throughput

0.559

High

924673

RS22B
Small ribosomal subunit protein uS8B

2

1

High-throughput

0.558

High

524783

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

527376

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

742135

HSP7F
Heat shock protein homolog SSE1

2

2

High-throughput

0.552

High

819449

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

755145

GCN1
eIF-2-alpha kinase activator GCN1

2

2

High-throughput

0.537

High

803157

ECM29
Proteasome component ECM29

2

2

High-throughput

0.537

High

435614

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.536

High

585995

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

810658

SSN3
Meiotic mRNA stability protein kinase SSN3

1

1

High-throughput

0.536

High

820383

RIO2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.536

High

917446

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

2

High-throughput

0.536

High

924663

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.536

High

503173

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

603093

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

843255

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

924620

CTK1
CTD kinase subunit alpha

1

0

High-throughput

0.513

High

924634

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.513

High

924645

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

433260

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.489

High

531835

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.489

High

570290

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.489

High

835854

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.489

High

924608

AP1M1
AP-1 complex subunit mu-1-I

1

1

High-throughput

0.489

High

924609

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.489

High

924617

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.489

High

919637

BUD32
EKC/KEOPS complex subunit BUD32

1

0

Small-scale

0.486

High

440962

CDC7
Cell division control protein 7

1

2

High-throughput

0.479

High

442045

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

455195

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

513145

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

513899

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.479

High

585335

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

682356

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

689096

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

753513

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

793510

MAK5
ATP-dependent RNA helicase MAK5

1

6

High-throughput

0.479

High

802886

DBP8
ATP-dependent RNA helicase DBP8

1

2

High-throughput

0.479

High

804735

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

808291

RRP8
25S rRNA

1

2

High-throughput

0.479

High

825547

UTP25
U3 small nucleolar RNA-associated protein 25

1

1

High-throughput

0.479

High

827574

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.479

High

852587

ROK1
ATP-dependent RNA helicase ROK1

1

1

High-throughput

0.479

High

863122

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

864494

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.479

High

897486

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.479

High

918881

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

918941

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

924168

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.479

High

924604

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

924616

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

924618

HAS1
ATP-dependent RNA helicase HAS1

1

6

High-throughput

0.479

High

924619

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

924630

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

924631

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

924648

RRP44
Exosome complex exonuclease DIS3

1

3

High-throughput

0.479

High

924662

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

924666

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

924667

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.479

High

924668

NOP56
Nucleolar protein 56

1

4

High-throughput

0.479

High

924669

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

670989

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

679938

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

738895

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

751453

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

758241

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

758397

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

804946

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

825069

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

836193

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

871113

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

874456

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

923052

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

923971

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

924629

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

924646

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

924649

NOP12
Nucleolar protein 12

1

0

High-throughput

0.458

High

924650

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

924658

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

924659

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

924660

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

924670

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

427393

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

383830

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

410267

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

419828

H2A2
Histone H2A.2

1

2

High-throughput

0.437

High

433774

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

504348

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

511256

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.437

High

513543

RL1A
Large ribosomal subunit protein uL1A

1

2

High-throughput

0.437

High

644966

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.437

High

645491

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.437

High

647178

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

709910

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

779309

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

792179

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.437

High

826043

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.437

High

924607

H3
Histone H3

1

5

High-throughput

0.437

High

924612

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.437

High

924654

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

924655

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.437

High

417160

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.426

High

453731

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

592421

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

916923

TAN1
tRNA acetyltransferase TAN1

1

2

Small-scale

0.417

High

893322

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.407

High

732180

COPG
Coatomer subunit gamma

2

0

High-throughput

0.324

High

743637

RTG2
Retrograde regulation protein 2

2

0

High-throughput

0.324

High

594499

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.305

High

826723

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

434185

RL36A
Large ribosomal subunit protein eL36A

1

0

High-throughput

0.279

Low

502664

RS25B
Small ribosomal subunit protein eS25B

1

0

High-throughput

0.279

Low

569838

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.279

Low

722153

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

917848

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.279

Low

923090

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

924024

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

924621

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

924639

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.279

Low

924653

DIA2
Protein DIA2

1

0

High-throughput

0.279

Low

924665

TPT1
tRNA 2'-phosphotransferase

1

0

High-throughput

0.279

Low

554527

RT13
Small ribosomal subunit protein mS27

1

0

High-throughput

0.269

Low

874333

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

High-throughput

0.269

Low

361010

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

436483

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

503826

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

514172

RS16B
Small ribosomal subunit protein uS9B

1

0

High-throughput

0.249

Low

514767

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

558822

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

598575

RGP1
Guanine nucleotide exchange factor subunit RGP1

1

0

High-throughput

0.249

Low

694611

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.249

Low

707846

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

735094

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

747980

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

778469

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

802310

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812546

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

823600

RIC1
Guanine nucleotide exchange factor subunit RIC1

1

0

High-throughput

0.249

Low

924605

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

924610

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

924613

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.249

Low

924615

ESP1
Separin

1

0

High-throughput

0.249

Low

924625

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

924636

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

924644

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

924651

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

924657

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.249

Low

394792

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

806985

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.232

Low

807252

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

836832

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

924628

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025