HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019904 - protein domain specific binding and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 249
+	Hs
		504883 HSP7C_HUMAN (26-637): 0: 916: 66.02		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310480 HSP7C_HUMAN (26-637): 0: 916: 66.02		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310479 BIP_HUMAN (19-654): 0: 914: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12