Protein: RS25A
Small ribosomal subunit protein eS25A (40S ribosomal protein S25-A) (RP45) (S31) (YS23)

Gene: RS25A, RPS25A
Organism: Saccharomyces cerevisiae S288C
Interactions: 121
UniProt ID: Q3E792

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol
GO:0022627 - cytosolic small ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

688966

RS5
Small ribosomal subunit protein uS7

3

3

Small-scale

0.827

High

820412

RIO2
Serine/threonine-protein kinase RIO2

3

4

Small-scale

0.827

High

514913

RS18A
Small ribosomal subunit protein uS13A

2

2

Small-scale

0.754

High

1084588

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.618

High

923170

BRE5
UBP3-associated protein BRE5

2

3

High-throughput

0.611

High

1030627

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

1

High-throughput

0.611

High

918746

PIL1
Sphingolipid long chain base-responsive protein PIL1

2

2

High-throughput

0.548

High

546914

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.536

High

1042421

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.536

High

558915

CAF20
Cap-associated protein CAF20

2

1

High-throughput

0.533

High

798366

ENP1
Essential nuclear protein 1

2

1

High-throughput

0.533

High

454506

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.489

High

150034

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

383971

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

435467

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

435656

RS9B
Small ribosomal subunit protein uS4B

1

3

High-throughput

0.479

High

436252

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

442195

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

455342

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.479

High

455458

RS19B
Small ribosomal subunit protein eS19B

1

4

High-throughput

0.479

High

482112

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

502764

RS21A
Small ribosomal subunit protein eS21A

1

2

High-throughput

0.479

High

503322

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

503533

RS28B
Small ribosomal subunit protein eS28B

1

2

High-throughput

0.479

High

504497

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

511710

RS23B
Small ribosomal subunit protein uS12B

1

1

High-throughput

0.479

High

511882

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.479

High

511977

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.479

High

512181

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

512737

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513304

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

513927

RS11B
Small ribosomal subunit protein uS17B

1

2

High-throughput

0.479

High

514208

RS16B
Small ribosomal subunit protein uS9B

1

2

High-throughput

0.479

High

570326

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.479

High

655538

RS3A2
Small ribosomal subunit protein eS1B

1

4

High-throughput

0.479

High

674919

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

680205

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

689745

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

747667

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.479

High

753674

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.479

High

778614

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

792335

GBLP
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.479

High

802469

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

802751

RS27B
Small ribosomal subunit protein eS27B

1

2

High-throughput

0.479

High

812028

RS14B
Small ribosomal subunit protein uS11B

1

3

High-throughput

0.479

High

815398

RS26A
Small ribosomal subunit protein eS26A

1

2

High-throughput

0.479

High

815447

RS26B
Small ribosomal subunit protein eS26B

1

2

High-throughput

0.479

High

831873

RS29A
Small ribosomal subunit protein uS14A

1

3

High-throughput

0.479

High

831898

RS29B
Small ribosomal subunit protein uS14B

1

3

High-throughput

0.479

High

858100

RSSA2
Small ribosomal subunit protein uS2B

1

4

High-throughput

0.479

High

861052

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.479

High

870698

RS7B
Small ribosomal subunit protein eS7B

1

3

High-throughput

0.479

High

874613

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

918511

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.479

High

1033655

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

1055540

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

1064848

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

1185389

RS21B
Small ribosomal subunit protein eS21B

1

2

High-throughput

0.479

High

1185391

RS28A
Small ribosomal subunit protein eS28A

1

2

High-throughput

0.479

High

1084653

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

2

High-throughput

0.464

High

383022

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

434673

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

502679

RS25B
Small ribosomal subunit protein eS25B

1

0

High-throughput

0.458

High

678771

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

Small-scale

0.458

High

806850

RPN10
26S proteasome regulatory subunit RPN10

1

0

Small-scale

0.458

High

814068

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

879911

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

1046339

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

1056580

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

1065049

VTS1
RNA-binding protein VTS1

1

0

High-throughput

0.458

High

825445

PRK1
Actin-regulating kinase PRK1

1

1

High-throughput

0.457

High

525695

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

528136

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

742779

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

820234

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

456559

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

1

High-throughput

0.437

High

557655

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

1

High-throughput

0.437

High

682440

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

732086

SYKM
Lysine--tRNA ligase, mitochondrial

1

1

High-throughput

0.437

High

803287

OTU2
OTU domain-containing protein 2

1

1

High-throughput

0.437

High

807941

BFR1
Nuclear segregation protein BFR1

1

1

High-throughput

0.437

High

809453

STM1
Suppressor protein STM1

1

1

High-throughput

0.437

High

812147

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.437

High

816984

BIM1
Protein BIM1

1

2

High-throughput

0.437

High

826129

ULP2
Ubiquitin-like-specific protease 2

1

1

Small-scale

0.437

High

844359

ELP2
Elongator complex protein 2

1

3

High-throughput

0.437

High

865815

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

871532

HGH1
Protein HGH1

1

1

Small-scale

0.437

High

923905

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

925438

FAP1
FKBP12-associated protein 1

1

2

High-throughput

0.437

High

1046877

TMA64
Translation machinery-associated protein 64

1

1

High-throughput

0.437

High

1059263

TSR1
Ribosome biogenesis protein TSR1

1

2

High-throughput

0.437

High

1064689

NAT5
N-alpha-acetyltransferase NAT5

1

2

High-throughput

0.437

High

1084503

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

826979

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

932664

ERG13
Hydroxymethylglutaryl-CoA synthase

1

0

High-throughput

0.279

Low

364837

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.249

Low

594663

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

666577

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.249

Low

678260

BUD23
18S rRNA

1

0

High-throughput

0.249

Low

705240

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

708655

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

735248

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

750811

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

780079

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

780915

YKH1
Uncharacterized oxidoreductase YKL071W

1

0

High-throughput

0.249

Low

789852

YC16
UPF0743 protein YCR087C-A

1

0

High-throughput

0.249

Low

803734

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

807210

IF1A
Eukaryotic translation initiation factor 1A

1

0

Small-scale

0.249

Low

818304

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.249

Low

824643

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

877953

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

916802

MAL11
General alpha-glucoside permease

1

0

High-throughput

0.249

Low

916828

YOR1
Oligomycin resistance ATP-dependent permease YOR1

1

0

High-throughput

0.249

Low

918624

SLX9
Ribosome biogenesis protein SLX9

1

0

Small-scale

0.249

Low

1031083

NOP3
Serine/arginine

1

0

High-throughput

0.249

Low

1054071

TMA10
Translation machinery-associated protein 10

1

0

High-throughput

0.249

Low

1056556

YL419
Putative ATP-dependent RNA helicase YLR419W

1

0

High-throughput

0.249

Low

1064315

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

1084432

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

1084978

ETFA
Probable electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025