HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~HSP70
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0051082 - unfolded protein binding
GO:0051085 - chaperone cofactor-dependent protein refolding
GO:0051087 - protein-folding chaperone binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024