HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: DJC16 (Q9Y2G8)
DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8)
Gene: DNAJC16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Hs			1 782
+	Mm
		588736 BIP_MOUSE (1-654): 0: 917: 98.62		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Hs
		243312 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJA2_HUMAN (27-374): 2.08e-45: 170: 18.01
+	Hs
		243275 HSP7C_HUMAN (26-637): 0: 916: 66.02		DNJA2_HUMAN (27-374): 2.08e-45: 170: 18.01
+	Hs
		714087 HS71L_HUMAN (24-647): 0: 922: 63.16		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		279280 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJB5_HUMAN (26-138): 1.25e-35: 140: 33.07
+	Hs
		636256 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJB1_HUMAN (26-135): 5.33e-36: 140: 36.04
+	Hs
		714088 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJB4_HUMAN (26-148): 1.06e-35: 140: 35.08
+	Hs
		681341 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJA1_HUMAN (26-213): 4.7e-35: 139: 26.98
+	Hs
		714084 HS71L_HUMAN (24-647): 0: 922: 63.16		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Rn
		419270 BIP_RAT (1-654): 0: 918: 98.47		DJB11_RAT (7-232): 6.28e-36: 141: 26.38
+	Mm
		588735 BIP_MOUSE (1-654): 0: 917: 98.62		DJB11_MOUSE (7-232): 5.76e-36: 141: 26.38
+	Hs
		279272 HSP7C_HUMAN (26-637): 0: 916: 66.02		DNJB5_HUMAN (26-138): 1.25e-35: 140: 33.07
+	Hs
		503463 HSP7C_HUMAN (26-637): 0: 916: 66.02		DNJB1_HUMAN (26-135): 5.33e-36: 140: 36.04
+	Hs
		714049 HS71L_HUMAN (24-647): 0: 922: 63.16		DNJA3_HUMAN (29-106): 3.89e-19: 93.2: 54.43
+	Rn
		419265 BIP_RAT (1-654): 0: 918: 98.47		DJC10_RAT (72-354): 1.9e-14: 79.6: 14.33
+	Mm
		588739 BIP_MOUSE (1-654): 0: 917: 98.62		DJC10_MOUSE (72-337): 4.23e-14: 78.4: 14.86
+	Hs
		423117 HSP7C_HUMAN (26-637): 0: 916: 66.02		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		503348 HSP7C_HUMAN (26-637): 0: 916: 66.02		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Rn
		419262 BIP_RAT (1-654): 0: 918: 98.47		PDIA4_RAT (121-255): 6.2e-09: 61.5: 15.00
+	Mm
		434692 BIP_MOUSE (1-654): 0: 917: 98.62		PDIA4_MOUSE (121-255): 6.01e-09: 61.5: 14.29