HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 2514
+	Hs
		87379 BIP_HUMAN (19-654): 0: 914: 100.00		C9JE98_HUMAN (1-2514): 0: 844: 96.99
+	Hs
		564205 HSP76_HUMAN (25-635): 0: 915: 62.54		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		502185 BIP_HUMAN (19-654): 0: 914: 100.00		TGO1_HUMAN (29-982): 1.96e-40: 167: 12.25
+	Hs
		504789 HSP7C_HUMAN (26-637): 0: 916: 66.02		MUC5B_HUMAN (493-2434): 5.45e-37: 157: 7.65
+	Hs
		504971 HSP7C_HUMAN (26-637): 0: 916: 66.02		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		504619 HSP7C_HUMAN (26-637): 0: 916: 66.02		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		505011 HSP7C_HUMAN (26-637): 0: 916: 66.02		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		504610 HSP7C_HUMAN (26-637): 0: 916: 66.02		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		502452 BIP_HUMAN (19-654): 0: 914: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		871747 HSP72_HUMAN (25-636): 0: 905: 64.51		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		871844 HSP72_HUMAN (25-636): 0: 905: 64.51		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		871744 HSP72_HUMAN (25-636): 0: 905: 64.51		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		504482 HSP7C_HUMAN (26-637): 0: 916: 66.02		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61
+	Sc
		560659 BIP_YEAST (22-638): 0: 798: 68.82		SEC31_YEAST (675-1102): 3.3e-11: 71.5: 16.07