Interactor 1: MYH3 (P11055)
Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE)
Gene: MYH3

Interactor 2: MYH4 (Q9Y623)
Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)
Gene: MYH4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myosin_head~Myosin_head, Myosin_N~Myosin_head, Myosin_head~Myosin_tail_1, Myosin_N~Myosin_tail_1, Myosin_tail_1~Myosin_tail_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005859 - muscle myosin complex
and 9 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1940
Hs

1 1939
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+ Dm
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+ Dm
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+ Ce
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+ Ce
+ Hs

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Last updated: 15 Jul 2024