HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: KAP2 (P13861)
cAMP-dependent protein kinase type II-alpha regulatory subunit
Gene: PRKAR2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 2147685
Identification Methods	affinity chromatography technology, biophysical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1827 Hs			1 404
+	Hs
		503267 MTAP2_HUMAN (1-1827): 0: 638: 100.00		KAP3_HUMAN (4-402): 1.97e-123: 365: 64.34
+	Hs
		496203 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP2_HUMAN (1-404): 6.63e-138: 401: 100.00
+	Hs
		496404 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP3_HUMAN (4-402): 1.97e-123: 365: 64.34
+	Bt
		337286 Q28869_BOVIN (1504-1827): 2.32e-44: 166: 97.53		KAP2_BOVIN (1-404): 1.94e-134: 392: 89.60
+	Bt
		679326 Q28869_BOVIN (1504-1827): 2.32e-44: 166: 97.53		KAP3_BOVIN (4-402): 1.18e-121: 360: 64.82
+	Hs
		313173 MAP1A_HUMAN (112-1821): 1.34e-37: 157: 9.61		RPGF3_HUMAN (241-390): 1.25e-30: 126: 24.36
+	Hs
		496157 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46