HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25192599, 29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 526
+	Hs
		504505 HSP7C_HUMAN (1-646): 0: 967: 100.00		RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10
+	Hs
		503920 HSP7C_HUMAN (1-646): 0: 967: 100.00		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		504960 HSP7C_HUMAN (1-646): 0: 967: 100.00		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Hs
		212099 HSP7C_HUMAN (1-646): 0: 967: 100.00		HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30
+	Hs
		871533 HSP72_HUMAN (2-646): 0: 940: 85.47		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		504019 HSP7C_HUMAN (1-646): 0: 967: 100.00		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		503332 HSP7C_HUMAN (1-646): 0: 967: 100.00		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		503745 HSP7C_HUMAN (1-646): 0: 967: 100.00		SC24C_HUMAN (1-262): 5.36e-11: 67.4: 14.34