HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32687490, 19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045296 - cadherin binding and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 896
+	Hs
		713920 HS71L_HUMAN (2-646): 0: 966: 82.48		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		504210 HSP7C_HUMAN (1-646): 0: 967: 100.00		FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35
+	Hs
		871601 HSP72_HUMAN (2-646): 0: 940: 85.47		FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35
+	Ce
		450542 HSP1_CAEEL (1-646): 0: 937: 84.39		Q9U2T9_CAEEL (5-425): 1.07e-23: 109: 11.85
+	Hs
		504890 HSP7C_HUMAN (1-646): 0: 967: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		504744 HSP7C_HUMAN (1-646): 0: 967: 100.00		EHD4_HUMAN (213-318): 5.77e-11: 68.2: 38.68