HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 619
+	Hs
		713949 HS71L_HUMAN (2-646): 0: 966: 82.48		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		564060 HSP76_HUMAN (6-646): 0: 955: 77.54		REL_HUMAN (1-619): 0: 692: 100.00
+	Mm
		978965 HS71A_MOUSE (1-646): 0: 954: 83.59		TF65_MOUSE (2-576): 1.99e-167: 490: 38.89
+	Hs
		503938 HSP7C_HUMAN (1-646): 0: 967: 100.00		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		713948 HS71L_HUMAN (2-646): 0: 966: 82.48		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		564059 HSP76_HUMAN (6-646): 0: 955: 77.54		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Mm
		638457 HS71A_MOUSE (1-646): 0: 954: 83.59		NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56
+	Hs
		503415 HSP7C_HUMAN (1-646): 0: 967: 100.00		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		587444 HS71L_HUMAN (2-646): 0: 966: 82.48		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		871536 HSP72_HUMAN (2-646): 0: 940: 85.47		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		564000 HSP76_HUMAN (6-646): 0: 955: 77.54		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		503913 HSP7C_HUMAN (1-646): 0: 967: 100.00		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		713946 HS71L_HUMAN (2-646): 0: 966: 82.48		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		587480 HSP72_HUMAN (2-646): 0: 940: 85.47		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		564058 HSP76_HUMAN (6-646): 0: 955: 77.54		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		503906 HSP7C_HUMAN (1-646): 0: 967: 100.00		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		713945 HS71L_HUMAN (2-646): 0: 966: 82.48		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		564057 HSP76_HUMAN (6-646): 0: 955: 77.54		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Dm
		505074 HSP7D_DROME (1-612): 0: 938: 86.60		NFKB1_DROME (8-347): 2.24e-105: 342: 32.60
+	Hs
		504030 HSP7C_HUMAN (1-646): 0: 967: 100.00		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84