HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043254 - regulation of protein-containing complex assembly and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 593
+	Hs
		489889 HSP7C_HUMAN (1-646): 0: 967: 100.00		PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85
+	Hs
		489911 HS71L_HUMAN (2-646): 0: 966: 82.48		PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85
+	Hs
		504648 HSP7C_HUMAN (1-646): 0: 967: 100.00		PTN18_HUMAN (231-579): 6.42e-111: 341: 32.32
+	Hs
		503394 HSP7C_HUMAN (1-646): 0: 967: 100.00		PTN2_HUMAN (263-518): 6.71e-51: 182: 39.00