HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: CDK10 (Q15131)
Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE)
Gene: CDK10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 360
+	Hs
		503460 HSP7C_HUMAN (1-646): 0: 967: 100.00		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		503423 HSP7C_HUMAN (1-646): 0: 967: 100.00		CD11B_HUMAN (30-353): 3.8e-132: 398: 53.64
+	Hs
		503902 HSP7C_HUMAN (1-646): 0: 967: 100.00		CDK3_HUMAN (36-330): 2.43e-137: 394: 43.92
+	Hs
		713942 HS71L_HUMAN (2-646): 0: 966: 82.48		CDK3_HUMAN (36-330): 2.43e-137: 394: 43.92
+	At
		612295 HS701_ARATH (3-646): 0: 944: 76.35		CDKA1_ARATH (36-326): 1.33e-129: 374: 43.00
+	Mm
		509463 HSP72_MOUSE (2-612): 0: 936: 87.77		CDK1_MOUSE (36-332): 8.11e-129: 372: 39.80
+	Hs
		503702 HSP7C_HUMAN (1-646): 0: 967: 100.00		CDK7_HUMAN (37-329): 5.56e-77: 242: 42.91
+	Hs
		564038 HSP76_HUMAN (6-646): 0: 955: 77.54		CDK7_HUMAN (37-329): 5.56e-77: 242: 42.91
+	Hs
		483754 HS71A_HUMAN (1-646): 0: 948: 84.37		CDK7_HUMAN (37-329): 5.56e-77: 242: 42.91