HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: NLRX1 (Q86UT6)
NLR family member X1 (Caterpiller protein 11.3) (CLR11.3) (Nucleotide-binding oligomerization domain protein 5) (Nucleotide-binding oligomerization domain protein 9)
Gene: NLRX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 975
+	Hs
		702468 HS71L_HUMAN (2-646): 0: 966: 82.48		C2TA_HUMAN (15-840): 2.01e-119: 394: 16.61
+	Hs
		504785 HSP7C_HUMAN (1-646): 0: 967: 100.00		NOD2_HUMAN (136-925): 1.42e-110: 368: 21.25
+	Hs
		714077 HS71L_HUMAN (2-646): 0: 966: 82.48		NOD2_HUMAN (136-925): 1.42e-110: 368: 21.25
+	Hs
		1120599 Q53FC7_HUMAN (6-646): 0: 951: 77.07		NOD1_HUMAN (136-908): 1.02e-101: 342: 18.05
+	Hs
		232772 HSP7C_HUMAN (1-646): 0: 967: 100.00		PHLP1_HUMAN (508-970): 2.46e-34: 145: 12.55
+	Hs
		503782 HSP7C_HUMAN (1-646): 0: 967: 100.00		NAL12_HUMAN (423-809): 4.4e-17: 88.7: 12.62
+	Hs
		886407 Q53FC7_HUMAN (6-646): 0: 951: 77.07		NAL12_HUMAN (423-809): 4.4e-17: 88.7: 12.62
+	Hs
		504345 HSP7C_HUMAN (1-646): 0: 967: 100.00		NLRC5_HUMAN (446-954): 6.46e-09: 62.5: 13.11
+	Hs
		714007 HS71L_HUMAN (2-646): 0: 966: 82.48		NLRC5_HUMAN (446-954): 6.46e-09: 62.5: 13.11