Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: BAG1 (Q99933)
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)
Gene: BAG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 25535373, 28215707, 12297498, 11741305, 19800331, 25416956, 9305631, 26871637, 11707401, 9873016, 17954934, 34428256, 20675402, 10671488, 12874020, 14978028, 11222862, 9774640
Identification Methods pull down, affinity chromatography technology, unspecified method, two hybrid, x-ray crystallography, two hybrid array, surface plasmon resonance, peptide array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BAG~HSP70
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 646
Hs

1 345
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024