HitPredict

Interactor 1: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 894
+	Hs
		674532 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		674528 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		665337 E41LA_HUMAN (207-833): 2.83e-126: 397: 25.41		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		546943 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		665554 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		EPHB2_HUMAN (2-837): 0: 605: 19.58
+	Hs
		665158 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		546957 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		TIE1_HUMAN (16-809): 4.24e-158: 494: 21.82
+	Hs
		505551 EPB41_HUMAN (1-864): 0: 781: 100.00		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		411302 PTN3_HUMAN (183-618): 3.39e-117: 380: 29.36		INSR_HUMAN (272-851): 1.65e-136: 443: 27.97
+	Hs
		983673 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83
+	Mm
		101476 FARP1_MOUSE (168-772): 8.98e-126: 406: 28.03		MET_MOUSE (536-799): 5.47e-66: 243: 45.90
+	Hs
		441435 PTN3_HUMAN (183-618): 3.39e-117: 380: 29.36		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		441450 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		547018 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83
+	Hs
		299238 FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		508287 FARP1_HUMAN (168-772): 1.31e-123: 400: 27.71		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		508209 E41LA_HUMAN (207-833): 2.83e-126: 397: 25.41		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		507828 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		507884 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435559 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07