Protein: HNF1A
Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)

Gene: HNF1A
Organism: Homo sapiens
Interactions: 83
UniProt ID: P20823

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

595909

HNF1B
Hepatocyte nuclear factor 1-beta

5

16

Small-scale

0.713

High

595955

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

4

6

Small-scale

0.694

High

595924

EP300
Histone acetyltransferase p300

3

20

Small-scale

0.664

High

595917

PHS
Pterin-4-alpha-carbinolamine dehydratase

5

6

Small-scale

0.659

High

595904

HNF1A
Hepatocyte nuclear factor 1-alpha

3

14

Small-scale

0.656

High

595964

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

2

8

Small-scale

0.637

High

595946

CBP
CREB-binding protein

2

20

Small-scale

0.624

High

595960

RNF14
E3 ubiquitin-protein ligase RNF14

1

1

Small-scale

0.594

High

595928

NCOA1
Nuclear receptor coactivator 1

1

9

Small-scale

0.561

High

595947

KAT2B
Histone acetyltransferase KAT2B

1

9

Small-scale

0.561

High

595948

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

6

Small-scale

0.561

High

595966

NCOA3
Nuclear receptor coactivator 3

1

13

Small-scale

0.561

High

320810

HS74L
Heat shock 70 kDa protein 4L

1

3

High-throughput

0.536

High

595908

HSP74
Heat shock 70 kDa protein 4

1

3

High-throughput

0.536

High

595911

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.536

High

449536

HMGB1
High mobility group protein B1

1

20

Small-scale

0.534

High

427441

ANXA2
Annexin A2

1

1

Small-scale

0.515

High

443326

VIME
Vimentin

1

2

Small-scale

0.515

High

453756

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.515

High

528536

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

Small-scale

0.515

High

595907

1433B
14-3-3 protein beta/alpha

1

6

Small-scale

0.515

High

595912

RANG
Ran-specific GTPase-activating protein

1

3

Small-scale

0.515

High

595916

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.515

High

595918

1433G
14-3-3 protein gamma

1

6

Small-scale

0.515

High

595919

1433E
14-3-3 protein epsilon

1

1

Small-scale

0.515

High

595920

1433Z
14-3-3 protein zeta/delta

1

6

Small-scale

0.515

High

595925

CBX3
Chromobox protein homolog 3

1

2

Small-scale

0.515

High

595930

SRSF7
Serine/arginine-rich splicing factor 7

1

6

Small-scale

0.515

High

595940

H2A2B
Histone H2A type 2-B

1

1

Small-scale

0.515

High

595945

PROX1
Prospero homeobox protein 1

1

1

Small-scale

0.515

High

595927

RYR3
Ryanodine receptor 3

1

1

High-throughput

0.512

High

546068

MYOG
Myogenin

1

4

Small-scale

0.501

High

595951

CDX2
Homeobox protein CDX-2

1

20

Small-scale

0.501

High

595922

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

3

High-throughput

0.500

High

595944

HS105
Heat shock protein 105 kDa

1

3

High-throughput

0.500

High

334132

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.493

High

595906

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

Small-scale

0.493

High

595915

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.493

High

595953

WN10A
Protein Wnt-10a

1

1

High-throughput

0.489

High

595923

TLE5
TLE family member 5

1

17

Small-scale

0.481

High

130315

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

20

Small-scale

0.479

High

152587

KMT2D
Histone-lysine N-methyltransferase 2D

1

19

High-throughput

0.479

High

183063

KDM6A
Lysine-specific demethylase 6A

1

5

High-throughput

0.479

High

345326

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

473467

ATX1L
Ataxin-1-like

1

8

High-throughput

0.479

High

572496

IBP3
Insulin-like growth factor-binding protein 3

1

1

Small-scale

0.479

High

595910

STAT3
Signal transducer and activator of transcription 3

1

3

Small-scale

0.479

High

595914

SMCA4
Transcription activator BRG1

1

12

Small-scale

0.479

High

595921

FABP5
Fatty acid-binding protein 5

1

2

High-throughput

0.479

High

595932

LIN9
Protein lin-9 homolog

1

2

High-throughput

0.479

High

595933

ZMYM4
Zinc finger MYM-type protein 4

1

7

High-throughput

0.479

High

595935

MCAF1
Activating transcription factor 7-interacting protein 1

1

15

High-throughput

0.479

High

595936

BCOR
BCL-6 corepressor

1

6

High-throughput

0.479

High

595937

PAXI1
PAX-interacting protein 1

1

13

High-throughput

0.479

High

595938

POGZ
Pogo transposable element with ZNF domain

1

3

High-throughput

0.479

High

595941

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

595942

KDM2B
Lysine-specific demethylase 2B

1

5

High-throughput

0.479

High

595950

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

595952

ARI3A
AT-rich interactive domain-containing protein 3A

1

18

High-throughput

0.479

High

595954

SP130
Histone deacetylase complex subunit SAP130

1

16

High-throughput

0.479

High

595956

SEBOX
Homeobox protein SEBOX

1

16

Small-scale

0.479

High

595958

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

595962

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

564799

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.458

High

595931

TCAL5
Transcription elongation factor A protein-like 5

1

0

High-throughput

0.458

High

595949

ZBED3
Zinc finger BED domain-containing protein 3

1

0

Small-scale

0.458

High

595963

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

0

Small-scale

0.458

High

333508

CYB5
Cytochrome b5

1

1

Small-scale

0.437

High

344161

A1AT
Alpha-1-antitrypsin

1

4

Small-scale

0.437

High

445152

IBP1
Insulin-like growth factor-binding protein 1

1

2

Small-scale

0.437

High

595926

HABP2
Hyaluronan-binding protein 2

1

2

Small-scale

0.437

High

595957

SGK2
Serine/threonine-protein kinase Sgk2

1

5

Small-scale

0.437

High

595929

IBP7
Insulin-like growth factor-binding protein 7

1

0

Small-scale

0.269

Low

595939

RHPN2
Rhophilin-2

1

0

High-throughput

0.269

Low

595965

SNX14
Sorting nexin-14

1

0

Small-scale

0.269

Low

199222

LEU1
Leukemia-associated protein 1

1

0

Small-scale

0.249

Low

595905

ADH6
Alcohol dehydrogenase 6

1

0

Small-scale

0.249

Low

595913

T4S4
Transmembrane 4 L6 family member 4

1

0

Small-scale

0.249

Low

595934

Q6FGD7
Tubulin-specific chaperone A

1

0

High-throughput

0.249

Low

595943

ASM3A
Cyclic GMP-AMP phosphodiesterase SMPDL3A

1

0

High-throughput

0.249

Low

595959

RM15
Large ribosomal subunit protein uL15m

1

0

Small-scale

0.249

Low

595961

SE1L1
Protein sel-1 homolog 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024