HitPredict

Interactor 1: PKHG3 (A1L390)
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene: PLEKHG3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36931259, 28514442
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 Hs			1 246
+	Hs
		50576 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		50581 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		50558 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		50574 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		50584 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		50561 PKHG3_HUMAN (1-1219): 0: 955: 100.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		905247 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982612 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		909883 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683603 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Mm
		926797 ARHG2_MOUSE (12-801): 2.66e-110: 371: 13.23		1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02
+	Hs
		927379 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		683534 ARG28_HUMAN (2-911): 5.12e-102: 358: 13.02		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647169 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		647099 ARG28_HUMAN (2-911): 5.12e-102: 358: 13.02		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904950 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982358 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		904845 ARG28_HUMAN (2-911): 5.12e-102: 358: 13.02		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		684253 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		684199 ARG28_HUMAN (2-911): 5.12e-102: 358: 13.02		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62