HitPredict

Interactor 1: PKHG3 (A1L390)
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene: PLEKHG3

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31586073
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~RhoGEF, BRCT~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0031267 - small GTPase binding
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024