Protein: GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1 (F-box and leucine-rich repeat protein GRR1) (F-box/LRR-repeat protein GRR1)

Gene: GRR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P24814

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000142 - cellular bud neck contractile ring
GO:0000209 - protein polyubiquitination
GO:0000751 - mitotic cell cycle G1 arrest in response to pheromone
GO:0004842 - ubiquitin-protein transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666699

SKP1
Suppressor of kinetochore protein 1

20

20

Small-scale

0.991

High

666716

CDC53
Cell division control protein 53

13

19

Small-scale

0.982

High

632407

CG12
G1/S-specific cyclin CLN2

10

3

Small-scale

0.755

High

632386

CG11
G1/S-specific cyclin CLN1

4

2

Small-scale

0.694

High

666713

RBX1
RING-box protein HRT1

4

6

Small-scale

0.690

High

666720

6P22
6-phosphofructo-2-kinase 2

3

1

Small-scale

0.647

High

364350

CDK1
Cyclin-dependent kinase 1

3

0

Small-scale

0.623

High

509413

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

10

High-throughput

0.618

High

666709

CYK2
Cytokinesis protein 2

2

3

Small-scale

0.611

High

666667

CDC48
Cell division control protein 48

2

2

High-throughput

0.594

High

666697

CTH2
mRNA decay factor CTH2

2

1

Small-scale

0.584

High

666673

TYE7
Transcription factor TYE7

2

0

Small-scale

0.569

High

666678

SRL3
Protein SRL3

2

0

Small-scale

0.559

High

666675

BMH2
Protein BMH2

1

8

Small-scale

0.552

High

666674

MKS1
Negative regulator of RAS-cAMP pathway

1

0

Small-scale

0.537

High

417032

VDAC1
Non-selective voltage-gated ion channel 1

1

3

High-throughput

0.536

High

575895

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.536

High

596915

PDC5
Pyruvate decarboxylase isozyme 2

1

1

High-throughput

0.536

High

598814

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.536

High

666668

PDC6
Pyruvate decarboxylase isozyme 3

1

1

High-throughput

0.536

High

666671

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.536

High

666686

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.536

High

666702

REG1
Resistance to glucose repression protein 1

1

0

Small-scale

0.529

High

666708

GIS4
Protein GIS4

1

0

Small-scale

0.529

High

574774

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

6

High-throughput

0.515

High

381412

H2B2
Histone H2B.2

1

0

High-throughput

0.513

High

666698

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

666705

COFI
Cofilin

1

0

High-throughput

0.513

High

666681

BZZ1
Protein BZZ1

1

2

High-throughput

0.508

High

666688

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

Small-scale

0.504

High

598960

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.500

High

408290

GAL1
Galactokinase

1

0

High-throughput

0.479

High

666680

STP2
Transcription factor STP2

1

1

Small-scale

0.479

High

666682

YHT1
PH domain-containing protein YHR131C

1

1

Small-scale

0.479

High

666703

STP1
Transcription factor STP1

1

1

Small-scale

0.479

High

666679

SHE3
SWI5-dependent HO expression protein 3

1

0

Small-scale

0.460

High

666706

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

Small-scale

0.460

High

666714

DSE3
Protein DSE3

1

0

Small-scale

0.460

High

666719

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.460

High

561248

CG13
G1/S-specific cyclin CLN3

1

0

Small-scale

0.458

High

666670

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

666672

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

666677

YK25
Uncharacterized protein YKR045C

1

0

Small-scale

0.458

High

666689

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

666694

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

666696

BUD4
Bud site selection protein 4

1

0

Small-scale

0.458

High

666704

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

Small-scale

0.458

High

666707

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

666715

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.458

High

666717

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

666718

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

666721

SFG1
Superficial pseudohyphal growth protein 1

1

0

Small-scale

0.458

High

666695

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.445

High

666684

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

666701

YNO4
Uncharacterized protein YNL144C

1

1

Small-scale

0.437

High

666711

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.407

High

666710

GIC2
GTPase-interacting component 2

2

0

Small-scale

0.306

High

666676

MTH1
Protein MTH1

2

0

Small-scale

0.305

High

666683

SSN2
Mediator of RNA polymerase II transcription subunit 13

2

0

Small-scale

0.304

High

367361

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

554882

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

555013

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

621339

METK2
S-adenosylmethionine synthase 2

1

0

High-throughput

0.261

Low

666692

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

666712

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

149195

FOB1
DNA replication fork-blocking protein FOB1

1

0

Small-scale

0.251

Low

666690

YIT6
Uncharacterized protein YIR016W

1

0

Small-scale

0.251

Low

666693

SSY5
SPS-sensor serine protease component SSY5

1

0

Small-scale

0.251

Low

666669

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

Small-scale

0.249

Low

666685

NPR2
Nitrogen permease regulator 2

1

0

Small-scale

0.249

Low

666687

FIR1
Factor interacting with REF2

1

0

Small-scale

0.249

Low

666691

SBE2
Protein SBE2

1

0

Small-scale

0.249

Low

666700

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025