HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 540
+	Hs
		507990 FGFR1_HUMAN (1-822): 0: 861: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		609274 FGFR3_HUMAN (6-821): 0: 730: 61.22		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		609282 FGFR3_HUMAN (6-821): 0: 730: 61.22		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		607960 FGFR4_HUMAN (29-808): 0: 664: 55.60		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		607963 FGFR4_HUMAN (29-808): 0: 664: 55.60		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		508210 FGFR1_HUMAN (1-822): 0: 861: 100.00		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		601598 FGFR2_HUMAN (1-821): 0: 803: 71.21		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		609552 FGFR3_HUMAN (6-821): 0: 730: 61.22		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		280018 FGFR3_HUMAN (6-821): 0: 730: 61.22		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		608144 FGFR4_HUMAN (29-808): 0: 664: 55.60		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		665433 EPHA3_HUMAN (3-775): 0: 643: 19.03		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		665663 EPHB2_HUMAN (4-819): 0: 640: 18.07		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		872493 EPHA5_HUMAN (3-791): 0: 639: 19.15		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		665667 EPHB2_HUMAN (4-819): 0: 640: 18.07		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		872496 EPHA5_HUMAN (3-791): 0: 639: 19.15		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		1072604 EPHA7_HUMAN (3-783): 0: 629: 19.40		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1072612 EPHA7_HUMAN (3-783): 0: 629: 19.40		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		872433 EPHA5_HUMAN (3-791): 0: 639: 19.15		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		1021499 EPHA7_HUMAN (3-783): 0: 629: 19.40		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		872639 EPHA4_HUMAN (3-783): 0: 620: 19.44		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51