Protein: DRONC
Caspase Dronc (EC 3.4.22.62) (Death regulator NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2]

Gene: DRONC
Organism: Drosophila melanogaster
Interactions: 31
UniProt ID: Q9XYF4

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173292

DIAP1
Death-associated inhibitor of apoptosis 1

12

20

Small-scale

0.980

High

144571

DRICE
Caspase drICE

7

18

Small-scale

0.966

High

1490362

DRONC
Caspase Dronc

3

19

Small-scale

0.845

High

1267327

APAF
Apoptosome protein Dark

3

1

Small-scale

0.646

High

633027

GLNA1
Glutamine synthetase 1, mitochondrial

2

0

High-throughput

0.547

High

1471591

Q9VDI1
LD46328p

2

0

High-throughput

0.547

High

1268063

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

2

High-throughput

0.541

High

1345103

Q8T092
LD21421p

1

0

High-throughput

0.518

High

1024301

LAMA
Laminin subunit alpha

1

1

High-throughput

0.494

High

121146

M9PF46
ribose-phosphate diphosphokinase

1

1

High-throughput

0.481

High

95189

E1JIE7
ubiquitinyl hydrolase 1

1

1

Small-scale

0.479

High

509820

UBIQP
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

1171556

MY31D
Unconventional myosin ID

1

2

Small-scale

0.479

High

1266382

Q7K4C2
LD46713p

1

2

High-throughput

0.479

High

1464827

MYO7A
Myosin-VIIa

1

1

Small-scale

0.479

High

1489885

UBR3
E3 ubiquitin-protein ligase Ubr3

1

2

Small-scale

0.479

High

1490004

Q9W418
GH17761p

1

4

Small-scale

0.479

High

1490363

R9PY16
Ubiquitin-like domain-containing protein

1

4

Small-scale

0.479

High

195182

O16043
Anon1A4

1

0

High-throughput

0.458

High

597788

NUMB
Protein numb

1

0

Small-scale

0.458

High

1262251

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

Small-scale

0.458

High

838639

TTKA
Protein tramtrack, alpha isoform

1

6

High-throughput

0.457

High

1485923

Q9VT32
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.457

High

1489153

Q9VZU6
BTB-VII protein domain

1

6

High-throughput

0.457

High

2683

A0A0B4LET0
Uncharacterized protein, isoform B

1

2

High-throughput

0.445

High

90900

F10A1
Hsc70-interacting protein 1

1

6

High-throughput

0.445

High

852540

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.445

High

1285909

F10A2
Hsc70-interacting protein 2

1

6

High-throughput

0.437

High

1024273

KCC2A
Calcium/calmodulin-dependent protein kinase type II alpha chain

1

0

Small-scale

0.426

High

197995

AMYR
Alpha-amylase-related protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025