HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: GOLI (Q86XS8)
E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)
Gene: RNF130

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36610398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 419
+	Hs
		508106 FGFR1_HUMAN (1-822): 0: 861: 100.00		RN149_HUMAN (25-343): 1.03e-80: 255: 41.85
+	Hs
		609400 FGFR3_HUMAN (6-821): 0: 730: 61.22		GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00
+	Hs
		601546 FGFR2_HUMAN (1-821): 0: 803: 71.21		RN149_HUMAN (25-343): 1.03e-80: 255: 41.85
+	Hs
		608031 FGFR4_HUMAN (29-808): 0: 664: 55.60		GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00
+	Hs
		872554 EPHB4_HUMAN (3-777): 2.12e-180: 546: 17.74		RN149_HUMAN (25-343): 1.03e-80: 255: 41.85
+	Hs
		665263 EPHA2_HUMAN (3-819): 0: 583: 18.68		RNF43_HUMAN (19-378): 1.06e-57: 203: 17.87
+	Hs
		385698 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50
+	Hs
		434242 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		RN149_HUMAN (25-343): 1.03e-80: 255: 41.85
+	Hs
		1031155 PTK7_HUMAN (162-385): 7.97e-17: 87.5: 17.39		RN128_HUMAN (1-384): 4.57e-89: 278: 36.90
+	Hs
		1031153 PTK7_HUMAN (162-385): 7.97e-17: 87.5: 17.39		RN149_HUMAN (25-343): 1.03e-80: 255: 41.85