Protein: PTN4
Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)

Gene: PTN4, PTPN4
Organism: Homo sapiens
Interactions: 58
UniProt ID: P29074

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663965

CRK
Adapter molecule crk

2

18

Small-scale

0.850

High

663981

MPP7
MAGUK p55 subfamily member 7

2

18

High-throughput

0.811

High

663966

CRKL
Crk-like protein

2

20

High-throughput

0.754

High

646653

1433T
14-3-3 protein theta

4

20

High-throughput

0.694

High

663969

1433G
14-3-3 protein gamma

4

20

High-throughput

0.694

High

663973

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.694

High

663976

1433F
14-3-3 protein eta

4

20

High-throughput

0.694

High

663983

KCD17
BTB/POZ domain-containing protein KCTD17

3

8

High-throughput

0.667

High

663962

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.656

High

663967

MK12
Mitogen-activated protein kinase 12

2

8

Small-scale

0.635

High

663993

SCML1
Sex comb on midleg-like protein 1

1

3

High-throughput

0.618

High

337358

ABL1
Tyrosine-protein kinase ABL1

1

20

High-throughput

0.618

High

412035

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.618

High

557617

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

655218

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

8

High-throughput

0.618

High

663961

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

15

High-throughput

0.618

High

663972

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

663970

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.611

High

663990

CADM1
Cell adhesion molecule 1

2

6

High-throughput

0.574

High

663986

KAT5
Histone acetyltransferase KAT5

1

2

High-throughput

0.568

High

643934

EF1G
Elongation factor 1-gamma

1

2

High-throughput

0.541

High

663964

ATRX
Transcriptional regulator ATRX

1

3

High-throughput

0.541

High

663974

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.541

High

330867

PAK4
Serine/threonine-protein kinase PAK 4

1

8

High-throughput

0.536

High

518823

TPR
Nucleoprotein TPR

1

10

High-throughput

0.536

High

663971

SMD1
Small nuclear ribonucleoprotein Sm D1

1

4

High-throughput

0.536

High

663978

CAPR1
Caprin-1

1

1

High-throughput

0.536

High

663994

SRRM2
Serine/arginine repetitive matrix protein 2

1

15

High-throughput

0.536

High

663977

NMDE1
Glutamate receptor ionotropic, NMDA 2A

2

19

Small-scale

0.521

High

263533

PR40A
Pre-mRNA-processing factor 40 homolog A

1

10

High-throughput

0.515

High

663968

CASP6
Caspase-6

1

1

High-throughput

0.515

High

515138

ADHX
Alcohol dehydrogenase class-3

1

0

High-throughput

0.513

High

663963

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.513

High

663982

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

378636

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

203180

GRID2
Glutamate receptor ionotropic, delta-2

1

20

Small-scale

0.504

High

195685

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

2

High-throughput

0.494

High

420657

LIPL
Lipoprotein lipase

1

1

High-throughput

0.494

High

663995

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.493

High

129375

GOLI4
Golgi integral membrane protein 4

1

11

High-throughput

0.489

High

581462

VCAM1
Vascular cell adhesion protein 1

1

11

High-throughput

0.489

High

663979

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

5

High-throughput

0.489

High

663984

SHKB1
SH3KBP1-binding protein 1

1

8

High-throughput

0.489

High

663992

ICAM5
Intercellular adhesion molecule 5

1

14

High-throughput

0.489

High

155786

UN13B
Protein unc-13 homolog B

1

5

High-throughput

0.479

High

176125

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.479

High

586578

CSK22
Casein kinase II subunit alpha'

1

5

High-throughput

0.479

High

663975

CSK21
Casein kinase II subunit alpha

1

7

High-throughput

0.479

High

663980

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

663988

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

2

High-throughput

0.479

High

663989

NP1L4
Nucleosome assembly protein 1-like 4

1

2

High-throughput

0.479

High

663991

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

527310

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

High-throughput

0.470

High

560381

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

663985

ZN418
Zinc finger protein 418

1

0

High-throughput

0.279

Low

413127

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

663987

ARK2N
Protein ARK2N

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024