HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 423
+	Hs
		508141 FGFR1_HUMAN (1-822): 0: 861: 100.00		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Hs
		609222 FGFR3_HUMAN (6-821): 0: 730: 61.22		AP3M2_HUMAN (3-422): 2.67e-123: 365: 25.81
+	Hs
		665310 EPHA2_HUMAN (3-819): 0: 583: 18.68		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Hs
		385470 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		AP1M1_HUMAN (1-423): 0: 528: 100.00
+	Hs
		507910 FGFR1_HUMAN (1-822): 0: 861: 100.00		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Mm
		546292 NTRK2_MOUSE (111-762): 1.43e-163: 497: 23.74		AP2M1_MOUSE (3-421): 3.27e-155: 447: 38.85
+	Hs
		608213 FGFR4_HUMAN (29-808): 0: 664: 55.60		STON1_HUMAN (125-423): 9.89e-68: 230: 19.43
+	Hs
		385759 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		AP3M1_HUMAN (3-422): 5.32e-127: 375: 26.73
+	Hs
		818906 EPHA5_HUMAN (3-791): 0: 639: 19.15		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Hs
		818944 EPHA7_HUMAN (3-783): 0: 629: 19.40		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Hs
		665450 EPHA8_HUMAN (3-819): 0: 603: 19.35		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Hs
		818949 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Hs
		384466 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72
+	Hs
		729245 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72