Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: SETMR (Q53H47)
Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.357); Transposon Hsmar1 transposase (EC 3.1.-.-)]
Gene: SETMAR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 18790802, 19458360
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000793 - condensed chromosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0042803 - protein homodimerization activity
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 684
+ Hs

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Last updated: 15 Jul 2024