Protein: ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate receptor) (IP-3-R) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)

Gene: ITPR1
Organism: Rattus norvegicus
Interactions: 19
UniProt ID: P29994

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0001666 - response to hypoxia
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005509 - calcium ion binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

716072

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

14

Small-scale

0.715

High

716078

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

3

3

Small-scale

0.664

High

591436

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

2

Small-scale

0.618

High

716077

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.536

High

716075

HAP1
Huntingtin-associated protein 1

1

3

Small-scale

0.529

High

716074

HD
Huntingtin

1

2

Small-scale

0.515

High

81556

ERLN2
Erlin-2

1

5

Small-scale

0.479

High

98688

F1LST4
Microtubule-associated protein

1

2

High-throughput

0.479

High

444708

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

6

Small-scale

0.479

High

444717

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

6

Small-scale

0.479

High

716073

TERA
Transitional endoplasmic reticulum ATPase

1

5

Small-scale

0.479

High

716076

NAC1
Sodium/calcium exchanger 1

1

1

Small-scale

0.479

High

716079

AKT3
RAC-gamma serine/threonine-protein kinase

1

2

High-throughput

0.479

High

716080

UBE4A
Ubiquitin conjugation factor E4 A

1

1

Small-scale

0.479

High

716081

Q6XD99
Spectrin beta chain

1

4

Small-scale

0.479

High

716082

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

2

Small-scale

0.479

High

98835

TRIO
Triple functional domain protein

1

4

Small-scale

0.445

High

619998

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High


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Last updated: 11Aug2025