HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.933

Property	Details
Experiments	25977368, 9371806, 9486535, 30995488, 14605208, unassigned4
Identification Methods	two hybrid, protein complementation assay, bimolecular fluorescence complementation, experimental interaction detection
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0008407 - chaeta morphogenesis GO:0046982 - protein heterodimerization activity GO:0061525 - hindgut development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 199
+	Mm
		1142448 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		Q6GTZ3_MOUSE (38-99): 8.25e-29: 106: 47.76
+	Mm
		781007 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Hs
		814913 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		780982 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Mm
		780945 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Mm
		589142 Q91XK1_MOUSE (219-661): 1.57e-133: 405: 34.81		ID1_MOUSE (38-99): 5.12e-29: 107: 47.76
+	Hs
		970599 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Mm
		1141284 ITF2_MOUSE (219-661): 1.83e-128: 397: 34.81		Q6GTZ3_MOUSE (38-99): 8.25e-29: 106: 47.76
+	Mm
		781009 Q91XK1_MOUSE (219-661): 1.57e-133: 405: 34.81		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Hs
		551089 ITF2_HUMAN (219-661): 1.83e-123: 384: 33.63		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		971137 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Mm
		781006 ITF2_MOUSE (219-661): 1.83e-128: 397: 34.81		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Hs
		551084 ITF2_HUMAN (219-661): 1.83e-123: 384: 33.63		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Mm
		780947 Q91XK1_MOUSE (219-661): 1.57e-133: 405: 34.81		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Hs
		551118 ITF2_HUMAN (219-661): 1.83e-123: 384: 33.63		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Mm
		780944 ITF2_MOUSE (219-661): 1.83e-128: 397: 34.81		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Hs
		551119 ITF2_HUMAN (219-661): 1.83e-123: 384: 33.63		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Hs
		551480 TFE2_HUMAN (219-663): 2.17e-109: 347: 31.77		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		551478 TFE2_HUMAN (219-663): 2.17e-109: 347: 31.77		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		551502 TFE2_HUMAN (219-663): 2.17e-109: 347: 31.77		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67