HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: Q9W4X2 (Q9W4X2)
Helix loop helix protein 3B (IP01280p)
Gene: HLH3B

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 376
+	Dm
		80865 DA_DROME (1-710): 0: 908: 100.00		DIMM_DROME (25-273): 3.8e-35: 134: 19.76
+	Dm
		509364 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (61-222): 2.18e-31: 122: 24.07
+	Dm
		496114 DA_DROME (1-710): 0: 908: 100.00		TWIST_DROME (96-264): 3.5e-28: 116: 25.67
+	Dm
		509377 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (134-263): 1.68e-27: 109: 26.15
+	Dm
		509380 DA_DROME (1-710): 0: 908: 100.00		Q9VL05_DROME (150-260): 8.57e-28: 109: 27.93
+	Dm
		509390 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (160-225): 4.14e-22: 94.4: 36.36
+	Mm
		1142072 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (116-241): 3.37e-30: 116: 26.98
+	Mm
		1142446 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (144-267): 4.76e-29: 113: 25.00
+	Mm
		603985 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (145-243): 1.49e-24: 104: 49.51
+	Hs
		210863 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF21_HUMAN (81-225): 2.71e-33: 124: 30.35
+	Hs
		546105 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYOG_HUMAN (89-276): 2.91e-31: 119: 21.43
+	Mm
		644476 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (162-226): 2.8e-22: 95.2: 41.54
+	Hs
		899129 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND2_HUMAN (116-241): 3.37e-30: 116: 26.98
+	Hs
		1018388 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF15_HUMAN (98-256): 1.06e-28: 112: 28.75
+	Hs
		330430 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND1_HUMAN (147-265): 1.49e-28: 112: 27.73
+	Hs
		616615 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYF6_HUMAN (79-229): 1.29e-27: 110: 21.85
+	Hs
		238594 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MUSC_HUMAN (81-233): 1.04e-26: 107: 23.86
+	Hs
		971805 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN1_HUMAN (139-222): 7.76e-27: 105: 42.86
+	Hs
		568226 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL1_HUMAN (145-229): 1.06e-24: 104: 56.32
+	Hs
		971838 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN2_HUMAN (172-222): 2.19e-20: 87.8: 64.71