HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: UBP13 (Q92995)
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)
Gene: USP13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.828

Property	Details
Experiments	24424410, 19615732
Identification Methods	pull down, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Hs			1 863
+	Mm
		476806 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP13_MOUSE (1-863): 0: 836: 95.94
+	Rn
		88579 UBC_RAT (1-102): 9.46e-29: 112: 31.13		D3ZDI9_RAT (1-863): 0: 825: 95.37
+	Hs
		800571 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		UBP5_HUMAN (26-863): 0: 740: 59.93
+	Rn
		88803 UBC_RAT (1-102): 9.46e-29: 112: 31.13		D3ZVQ0_RAT (26-863): 0: 747: 60.63
+	Mm
		476724 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP5_MOUSE (26-863): 0: 744: 60.51
+	Dm
		547964 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		Q9VZU7_DROME (26-860): 0: 611: 43.16
+	Mm
		69894 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP24_MOUSE (295-815): 5.09e-79: 282: 13.21
+	Rn
		94096 UBC_RAT (1-102): 9.46e-29: 112: 31.13		F1LSM0_RAT (295-815): 1.21e-78: 281: 13.21
+	Hs
		924100 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		USP9X_HUMAN (296-701): 3.34e-69: 252: 16.86
+	Mm
		476727 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP25_MOUSE (336-854): 2.73e-71: 256: 17.72
+	Rn
		89001 UBC_RAT (1-102): 9.46e-29: 112: 31.13		D4ACD3_RAT (336-854): 1.02e-70: 254: 17.60
+	Rn
		88542 UBC_RAT (1-102): 9.46e-29: 112: 31.13		D3ZC84_RAT (296-701): 3.59e-69: 252: 16.63
+	Mm
		476759 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		USP9X_MOUSE (296-701): 3.7e-69: 252: 16.63
+	Rn
		1137288 UBC_RAT (1-102): 9.46e-29: 112: 31.13		UBP2_RAT (713-859): 2.41e-23: 107: 17.11
+	Mm
		476793 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP19_MOUSE (719-863): 1.16e-22: 106: 16.25
+	Mm
		476865 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP8_MOUSE (698-861): 2.41e-20: 98.9: 12.94
+	Mm
		476898 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP44_MOUSE (688-863): 7.27e-15: 80.8: 14.14
+	Sc
		408408 RS31_YEAST (1-122): 3.56e-31: 111: 29.51		UBP8_YEAST (717-859): 2.7e-14: 78.5: 15.29
+	Rn
		70290 UBC_RAT (1-102): 9.46e-29: 112: 31.13		UBP4_RAT (501-606): 2.99e-10: 66.4: 20.18
+	Mm
		476695 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		UBP4_MOUSE (501-606): 3.12e-10: 66: 19.27