Protein: BDF1
Bromodomain-containing factor 1

Gene: BDF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 167
UniProt ID: P35817

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000812 - Swr1 complex
GO:0001046 - core promoter sequence-specific DNA binding
GO:0001094 - TFIID-class transcription factor complex binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

777129

BDF2
Bromodomain-containing factor 2

8

19

Small-scale

0.971

High

736632

ASF1
Histone chaperone ASF1

2

5

Small-scale

0.768

High

777119

SWR1
Helicase SWR1

16

20

Small-scale

0.759

High

382022

H4
Histone H4

9

20

Small-scale

0.751

High

777100

RSC4
Chromatin structure-remodeling complex subunit RSC4

2

18

High-throughput

0.737

High

777131

RSC58
Chromatin structure-remodeling complex protein RSC58

2

3

High-throughput

0.737

High

777148

H2AZ
Histone H2A.Z

6

20

Small-scale

0.727

High

777093

H3
Histone H3

6

20

Small-scale

0.724

High

777110

RUVB1
RuvB-like protein 1

6

10

Small-scale

0.719

High

777042

SWC5
SWR1-complex protein 5

4

2

Small-scale

0.691

High

777090

AF9
Protein AF-9 homolog

4

4

Small-scale

0.687

High

777117

TAF7
Transcription initiation factor TFIID subunit 7

3

10

Small-scale

0.682

High

777085

SWC4
SWR1-complex protein 4

4

3

Small-scale

0.676

High

777143

RUVB2
RuvB-like protein 2

4

10

Small-scale

0.676

High

777081

SKP1
Suppressor of kinetochore protein 1

1

2

High-throughput

0.656

High

777128

SWC7
SWR1-complex protein 7

4

0

Small-scale

0.649

High

585903

CSK21
Casein kinase II subunit alpha

3

20

Small-scale

0.640

High

622922

CSK22
Casein kinase II subunit alpha'

3

20

Small-scale

0.640

High

777096

ARP4
Actin-related protein 4

3

20

Small-scale

0.640

High

777145

ARP6
Actin-like protein ARP6

3

16

Small-scale

0.640

High

777108

VPS71
Vacuolar protein sorting-associated protein 71

3

0

Small-scale

0.634

High

381062

H2B1
Histone H2B.1

3

20

High-throughput

0.633

High

777109

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

2

16

Small-scale

0.626

High

777088

PRS10
26S proteasome subunit RPT4

1

8

High-throughput

0.621

High

777101

SPP1
COMPASS component SPP1

1

20

High-throughput

0.621

High

679556

CDC48
Cell division control protein 48

1

12

High-throughput

0.618

High

743078

STH1
Nuclear protein STH1/NPS1

1

20

High-throughput

0.618

High

777057

ATAD2
ATPase histone chaperone YTA7

1

14

High-throughput

0.618

High

777124

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.618

High

725959

SWC3
SWR1-complex protein 3

3

0

Small-scale

0.614

High

777074

TAF1
Transcription initiation factor TFIID subunit 1

2

13

Small-scale

0.612

High

561463

TBP
TATA-box-binding protein

2

10

Small-scale

0.611

High

739591

SPT16
FACT complex subunit SPT16

2

9

High-throughput

0.601

High

381483

H2B2
Histone H2B.2

2

20

High-throughput

0.584

High

777092

ACT
Actin

2

15

Small-scale

0.584

High

777106

VPS72
Vacuolar protein sorting-associated protein 72

2

1

Small-scale

0.584

High

777138

SCC1
Sister chromatid cohesion protein 1

2

3

High-throughput

0.584

High

777045

YNG2
Chromatin modification-related protein YNG2

1

20

Small-scale

0.575

High

777105

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.575

High

647748

RFA1
Replication factor A protein 1

1

5

Small-scale

0.561

High

777056

TBP6
Probable 26S proteasome subunit YTA6

1

8

High-throughput

0.555

High

777082

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

13

Small-scale

0.554

High

777133

ESA1
Histone acetyltransferase ESA1

2

20

Small-scale

0.552

High

777046

CSK2C
Casein kinase II subunit beta'

2

10

Small-scale

0.533

High

777071

CSK2B
Casein kinase II subunit beta

2

10

Small-scale

0.533

High

777135

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

8

High-throughput

0.515

High

752103

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.514

High

777048

SSN3
Meiotic mRNA stability protein kinase SSN3

1

20

Small-scale

0.501

High

602041

KAR3
Kinesin-like protein KAR3

1

7

High-throughput

0.481

High

646015

KIN3
Serine/threonine-protein kinase KIN3

1

11

High-throughput

0.481

High

755222

NUF2
Kinetochore protein NUF2

1

5

High-throughput

0.481

High

777041

FL2D
Protein MUM2

1

1

High-throughput

0.481

High

777058

RAD26
DNA repair and recombination protein RAD26

1

20

High-throughput

0.481

High

777062

MAD1
Spindle assembly checkpoint component MAD1

1

20

High-throughput

0.481

High

777073

SAC3
Nuclear mRNA export protein SAC3

1

4

High-throughput

0.481

High

777075

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

3

High-throughput

0.481

High

777080

TEA1
TY1 enhancer activator

1

3

High-throughput

0.481

High

777097

SEN1
Helicase SEN1

1

9

High-throughput

0.481

High

777103

HOT1
High-osmolarity-induced transcription protein 1

1

1

High-throughput

0.481

High

777134

MDN1
Midasin

1

20

High-throughput

0.481

High

408407

GAL4
Regulatory protein GAL4

1

4

Small-scale

0.479

High

419693

H2A2
Histone H2A.2

1

20

High-throughput

0.479

High

436373

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

3

High-throughput

0.479

High

444845

SIR3
Regulatory protein SIR3

1

8

High-throughput

0.479

High

448952

TOP2
DNA topoisomerase 2

1

15

High-throughput

0.479

High

473519

LEUR
Regulatory protein LEU3

1

4

Small-scale

0.479

High

550046

RAP1
DNA-binding protein RAP1

1

1

Small-scale

0.479

High

594307

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

8

High-throughput

0.479

High

646367

RAD53
Serine/threonine-protein kinase RAD53

1

3

High-throughput

0.479

High

678313

RSC6
Chromatin structure-remodeling complex protein RSC6

1

20

High-throughput

0.479

High

688738

RFA2
Replication factor A protein 2

1

3

Small-scale

0.479

High

706746

TF2B
Transcription initiation factor IIB

1

10

High-throughput

0.479

High

708712

TF3B
Transcription factor IIIB 70 kDa subunit

1

10

High-throughput

0.479

High

709683

BMH1
Protein BMH1

1

4

High-throughput

0.479

High

744280

CHD1
Chromo domain-containing protein 1

1

20

High-throughput

0.479

High

744823

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

11

High-throughput

0.479

High

745574

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

3

High-throughput

0.479

High

757756

SAS3
Histone acetyltransferase SAS3

1

20

High-throughput

0.479

High

777040

LDB7
Chromatin structure-remodeling complex protein RSC14

1

1

High-throughput

0.479

High

777043

RSC30
Chromatin structure-remodeling complex protein RSC30

1

4

High-throughput

0.479

High

777070

RSC8
Chromatin structure-remodeling complex protein RSC8

1

20

High-throughput

0.479

High

777087

RT102
Regulator of Ty1 transposition protein 102

1

2

High-throughput

0.479

High

777091

APJ1
J domain-containing protein APJ1

1

16

High-throughput

0.479

High

777102

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

2

High-throughput

0.479

High

777112

IOC4
ISWI one complex protein 4

1

1

High-throughput

0.479

High

777115

POB3
FACT complex subunit POB3

1

12

High-throughput

0.479

High

777118

ARP9
Actin-like protein ARP9

1

20

High-throughput

0.479

High

777121

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

10

High-throughput

0.479

High

777122

PDP3
NuA3 HAT complex component PDP3

1

10

High-throughput

0.479

High

777125

RSC3
Chromatin structure-remodeling complex protein RSC3

1

4

High-throughput

0.479

High

777136

IOC2
ISWI one complex protein 2

1

1

High-throughput

0.479

High

777137

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

3

High-throughput

0.479

High

777139

NTO1
NuA3 HAT complex component NTO1

1

19

High-throughput

0.479

High

777142

ARP7
Actin-related protein 7

1

20

High-throughput

0.479

High

777146

CMR1
DNA damage-binding protein CMR1

1

20

High-throughput

0.479

High

777151

HTL1
High temperature lethal protein 1

1

1

High-throughput

0.479

High

454035

GCR1
Glycolytic genes transcriptional activator GCR1

1

0

High-throughput

0.460

High

760549

SCD5
Protein SCD5

1

0

High-throughput

0.460

High

777053

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

777059

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

777065

REF2
RNA end formation protein 2

1

0

High-throughput

0.460

High

777079

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

777114

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.460

High

653789

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.458

High

688789

RFA3
Replication factor A protein 3

1

0

Small-scale

0.458

High

689773

INO2
Protein INO2

1

0

Small-scale

0.458

High

777054

FLO8
Transcriptional activator FLO8

1

0

Small-scale

0.458

High

777069

IES1
Ino eighty subunit 1

1

0

Small-scale

0.458

High

777120

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

777132

RBX1
RING-box protein HRT1

1

2

High-throughput

0.457

High

523569

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

526371

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

544416

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

670563

SIS1
Protein SIS1

1

12

High-throughput

0.445

High

741321

HSP7F
Heat shock protein homolog SSE1

1

18

High-throughput

0.445

High

754201

MSN4
Zinc finger protein MSN4

1

11

High-throughput

0.445

High

777049

CAJ1
Protein CAJ1

1

19

High-throughput

0.445

High

777144

CAF1A
Chromatin assembly factor 1 subunit A

1

8

High-throughput

0.445

High

477545

MYO1
Myosin-1

1

11

High-throughput

0.439

High

758075

CASP
Protein CASP

1

14

High-throughput

0.439

High

777037

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.439

High

777038

EBP2
rRNA-processing protein EBP2

1

3

High-throughput

0.439

High

777044

LAM4
Membrane-anchored lipid-binding protein LAM4

1

3

High-throughput

0.439

High

777047

END3
Actin cytoskeleton-regulatory complex protein END3

1

3

High-throughput

0.439

High

777055

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

3

High-throughput

0.439

High

777066

GCN20
Protein GCN20

1

9

High-throughput

0.439

High

777077

SNX4
Sorting nexin-4

1

6

High-throughput

0.439

High

777084

ERP6
Protein ERP6

1

1

High-throughput

0.439

High

777098

SED5
Integral membrane protein SED5

1

1

High-throughput

0.439

High

777099

MDM1
Structural protein MDM1

1

2

High-throughput

0.439

High

777107

VPS60
Vacuolar protein-sorting-associated protein 60

1

5

High-throughput

0.439

High

777113

VPS20
Vacuolar protein sorting-associated protein 20

1

5

High-throughput

0.439

High

777127

YSP2
Membrane-anchored lipid-binding protein YSP2

1

3

High-throughput

0.439

High

777130

YET3
Endoplasmic reticulum transmembrane protein 3

1

1

High-throughput

0.439

High

777149

VPS5
Vacuolar protein sorting-associated protein 5

1

6

High-throughput

0.439

High

777150

YO338
SWIRM domain-containing protein YOR338W

1

0

High-throughput

0.438

High

777060

MAM33
Mitochondrial acidic protein MAM33

1

5

High-throughput

0.437

High

777052

EAF5
Chromatin modification-related protein EAF5

1

0

Small-scale

0.426

High

777061

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

3

High-throughput

0.417

High

510372

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.407

High

777126

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

9

High-throughput

0.407

High

777140

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

777039

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.269

Low

673629

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.251

Low

755055

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

777051

SSO2
Protein SSO2

1

0

High-throughput

0.251

Low

777063

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.251

Low

777064

BUD6
Bud site selection protein 6

1

0

High-throughput

0.251

Low

777067

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

777068

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

777072

FAR3
Factor arrest protein 3

1

0

High-throughput

0.251

Low

777076

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

777078

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

777083

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

777086

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.251

Low

777089

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.251

Low

777094

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.251

Low

777095

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

777104

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

0

High-throughput

0.251

Low

777111

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

777116

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

777123

MMR1
Mitochondrial MYO2 receptor-related protein 1

1

0

High-throughput

0.251

Low

777141

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

777147

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.251

Low

777050

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

740776

STE14
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.238

Low

748160

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025