HitPredict

Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: TIM23 (P32897)
Mitochondrial import inner membrane translocase subunit TIM23 (Membrane import machinery protein MIM23) (Mitochondrial protein import protein 3) (Mitochondrial protein import protein MAS6)
Gene: TIM23

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	23864706, 9171336, 25792736, 14981507, 10393182, 15797382, 15992824, 16107694, 14532110, 25008211, 32130909, 25124039
Identification Methods	affinity chromatography technology, pull down, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex GO:0006886 - intracellular protein transport GO:0030150 - protein import into mitochondrial matrix
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 654 Sc			1 222
+	Sc
		746845 HSP7E_YEAST (17-646): 0: 969: 82.22		TIM23_YEAST (1-222): 3.6e-82: 245: 100.00
+	Sc
		510498 HSP77_YEAST (1-654): 0: 896: 100.00		TIM17_YEAST (102-211): 4.46e-33: 118: 23.64
+	Sc
		746947 HSP7Q_YEAST (12-637): 0: 585: 52.08		TIM23_YEAST (1-222): 3.6e-82: 245: 100.00