HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: FES1 (P38260)
Hsp70 nucleotide exchange factor FES1 (Factor exchange for SSA1 protein 1)
Gene: FES1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	27001512, 17132105, 31806703, 22635919, 24671421, 19536198
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 290
+	Sc
		747187 SSB2_YEAST (1-613): 0: 1118: 99.35		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Hs
		564199 HSP76_HUMAN (3-612): 0: 901: 58.66		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		504872 HSP7C_HUMAN (5-612): 0: 900: 59.84		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		483807 HS71B_HUMAN (5-611): 0: 897: 59.93		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		714085 HS71L_HUMAN (5-612): 0: 896: 59.34		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		871809 HSP72_HUMAN (4-612): 0: 891: 59.97		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Sp
		195082 HSP71_SCHPO (6-612): 0: 875: 59.77		FES1_SCHPO (1-237): 8.83e-52: 173: 29.63
+	Sc
		605341 HSP74_YEAST (9-611): 0: 681: 62.15		FES1_YEAST (1-290): 1.29e-112: 328: 100.00