Protein: SIF2
SIR4-interacting protein SIF2

Gene: SIF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P38262

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

781735

SET3
SET domain-containing protein 3

8

20

Small-scale

0.965

High

671412

RNA14
mRNA 3'-end-processing protein RNA14

2

16

High-throughput

0.762

High

796839

HOS4
Protein HOS4

8

15

Small-scale

0.752

High

672763

SNT1
Probable DNA-binding protein SNT1

7

20

Small-scale

0.747

High

575932

CYPH
Peptidyl-prolyl cis-trans isomerase

7

3

Small-scale

0.744

High

796842

HOS2
Probable histone deacetylase HOS2

5

18

Small-scale

0.712

High

796844

HST1
NAD-dependent protein deacetylase HST1

4

5

Small-scale

0.687

High

796852

IMB1
Importin subunit beta-1

2

5

High-throughput

0.621

High

511085

YRF13
Y' element ATP-dependent helicase protein 1 copy 3

1

2

High-throughput

0.618

High

796836

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

Small-scale

0.618

High

796847

H3
Histone H3

1

7

High-throughput

0.618

High

796855

HSH49
Protein HSH49

2

10

High-throughput

0.590

High

796841

ZDS1
Protein ZDS1

2

4

High-throughput

0.567

High

523749

HSP71
Heat shock protein SSA1

2

12

High-throughput

0.552

High

526526

HSP72
Heat shock protein SSA2

2

12

High-throughput

0.552

High

544648

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.552

High

747121

RT04
Small ribosomal subunit protein uS2m

2

4

High-throughput

0.539

High

721887

XPO1
Exportin-1

1

10

High-throughput

0.536

High

796849

IMA1
Importin subunit alpha

1

7

High-throughput

0.536

High

796851

UTP21
U3 small nucleolar RNA-associated protein 21

1

18

High-throughput

0.536

High

796840

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.518

High

511091

YRF17
Y' element ATP-dependent helicase protein 1 copy 7

1

2

High-throughput

0.514

High

590613

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

675950

MAS5
Mitochondrial protein import protein MAS5

1

14

High-throughput

0.500

High

603458

VATA
V-type proton ATPase catalytic subunit A

1

12

High-throughput

0.489

High

796845

ZDS2
Protein ZDS2

1

7

High-throughput

0.489

High

796843

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.486

High

706924

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

739613

SPT16
FACT complex subunit SPT16

1

8

High-throughput

0.479

High

747820

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

796854

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.479

High

678670

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

1

High-throughput

0.457

High

367010

ATPB
ATP synthase subunit beta, mitochondrial

1

11

High-throughput

0.457

High

367741

ENO1
Enolase 1

1

4

High-throughput

0.457

High

405081

LEU3
3-isopropylmalate dehydrogenase

1

5

High-throughput

0.457

High

619353

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.457

High

670621

SIS1
Protein SIS1

1

14

High-throughput

0.445

High

741456

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

796838

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

796848

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

796846

DNM1
Dynamin-related protein DNM1

1

3

High-throughput

0.407

High

550651

SIR4
Regulatory protein SIR4

3

0

Small-scale

0.344

High

796837

AVT2
Vacuolar amino acid transporter 2

1

0

High-throughput

0.279

Low

796850

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.279

Low

796853

TRM3
tRNA

1

0

High-throughput

0.279

Low

784479

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025