Protein: HIR2
Protein HIR2 (Histone transcription regulator 2)

Gene: HIR2
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P32480

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000417 - HIR complex
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

690827

HIR1
Protein HIR1

6

17

Small-scale

0.943

High

689847

ASF1
Histone chaperone ASF1

7

16

Small-scale

0.743

High

690887

HPC2
Histone promoter control protein 2

4

5

Small-scale

0.691

High

690878

RT106
Histone chaperone RTT106

3

2

Small-scale

0.660

High

690883

HIR3
Histone transcription regulator 3

3

3

Small-scale

0.656

High

356327

H4
Histone H4

3

10

Small-scale

0.633

High

690885

H3
Histone H3

3

20

Small-scale

0.633

High

490648

HSP71
Heat shock protein SSA1

2

15

High-throughput

0.611

High

365982

HSP82
ATP-dependent molecular chaperone HSP82

2

13

High-throughput

0.571

High

690866

HSP7F
Heat shock protein homolog SSE1

2

20

High-throughput

0.571

High

690870

SPT10
Protein SPT10

2

2

High-throughput

0.571

High

690877

SSB2
Ribosome-associated molecular chaperone SSB2

2

17

High-throughput

0.552

High

392082

H2A1
Histone H2A.1

1

8

High-throughput

0.536

High

510618

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.536

High

577138

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

9

Small-scale

0.515

High

603287

SNF2
Transcription regulatory protein SNF2

1

16

Small-scale

0.515

High

690867

SWI3
SWI/SNF complex subunit SWI3

1

7

Small-scale

0.515

High

367855

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.479

High

607230

RFA1
Replication factor A protein 1

1

7

Small-scale

0.479

High

624676

CG22
G2/mitotic-specific cyclin-2

1

1

Small-scale

0.479

High

633042

MAS5
Mitochondrial protein import protein MAS5

1

11

High-throughput

0.479

High

661637

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

687665

BTAF1
TATA-binding protein-associated factor MOT1

1

19

Small-scale

0.479

High

690868

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

7

High-throughput

0.479

High

690871

CENPA
Histone H3-like centromeric protein CSE4

1

20

Small-scale

0.479

High

690884

TAF4
Transcription initiation factor TFIID subunit 4

1

3

High-throughput

0.479

High

690880

DLS1
Protein DLS1

1

0

High-throughput

0.458

High

690882

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

690888

UBC7
Ubiquitin-conjugating enzyme E2 7

1

7

High-throughput

0.457

High

355397

H2B1
Histone H2B.1

1

15

High-throughput

0.445

High

392349

H2A2
Histone H2A.2

1

8

High-throughput

0.445

High

493458

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

627817

SIS1
Protein SIS1

1

11

High-throughput

0.445

High

690872

SET3
SET domain-containing protein 3

1

14

High-throughput

0.445

High

690875

SSZ1
Ribosome-associated complex subunit SSZ1

1

10

High-throughput

0.445

High

690876

MBP1
Transcription factor MBP1

1

5

High-throughput

0.445

High

690879

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.445

High

690881

DJP1
DnaJ-like protein 1

1

12

High-throughput

0.445

High

690886

SEN1
Helicase SEN1

1

8

Small-scale

0.445

High

690889

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

19

High-throughput

0.445

High

690892

RLF2
Chromatin assembly factor 1 subunit p90

1

9

High-throughput

0.445

High

690873

KMO
Kynurenine 3-monooxygenase

1

2

High-throughput

0.437

High

419318

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

690865

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

690890

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

690869

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

690874

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.407

High

690891

HSP42
Heat shock protein 42

1

3

High-throughput

0.407

High


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Last updated: 15 Jul 2024