HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: PPID (P53691)
Peptidyl-prolyl cis-trans isomerase CPR6 (PPIase CPR6) (EC 5.2.1.8) (Rotamase CPR6)
Gene: CPR6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25380751, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0042026 - protein refolding GO:0051082 - unfolded protein binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 371
+	Sc
		769059 SSB2_YEAST (1-613): 0: 1118: 99.35		PPID_YEAST (1-371): 4.51e-121: 356: 100.00
+	Sc
		511858 SSB1_YEAST (1-613): 0: 1128: 100.00		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		768821 SSB2_YEAST (1-613): 0: 1118: 99.35		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		510442 SSB1_YEAST (1-613): 0: 1128: 100.00		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Sc
		510122 SSB1_YEAST (1-613): 0: 1128: 100.00		CYPH_YEAST (5-174): 3.55e-77: 236: 55.88
+	Sc
		540585 SSB2_YEAST (1-613): 0: 1118: 99.35		CYPH_YEAST (5-174): 3.55e-77: 236: 55.88
+	Hs
		503968 HSP7C_HUMAN (5-612): 0: 900: 59.84		PPID_HUMAN (2-371): 4.59e-130: 379: 43.51
+	Hs
		503513 HSP7C_HUMAN (5-612): 0: 900: 59.84		PPIF_HUMAN (3-174): 2.09e-77: 238: 54.07
+	Ca
		784139 HSP71_CANAL (9-594): 0: 670: 63.37		PPID_CANAL (1-371): 1.5e-119: 352: 51.07
+	Sc
		605366 HSP74_YEAST (9-611): 0: 681: 62.15		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		450095 HSP73_YEAST (9-611): 0: 677: 60.66		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		605308 HSP74_YEAST (9-611): 0: 681: 62.15		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Sc
		449937 HSP73_YEAST (9-611): 0: 677: 60.66		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88