Interactor 1: ZBT7C (A1YPR0)
Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)
Gene: ZBTB7C

Interactor 2: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 22331133
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 619
Hs

1 1147
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024