HitPredict

Interactor 1: PYC (P11498)
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Gene: PC

Interactor 2: ARF3 (P61204)
ADP-ribosylation factor 3
Gene: ARF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1178 Hs			1 181
+	Hs
		513564 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		513529 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Hs
		950605 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		574662 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Hs
		135983 ACACB_HUMAN (1-742): 5.49e-175: 572: 23.27		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Sc
		424334 PYR1_YEAST (19-420): 2.78e-58: 223: 16.83		ARF2_YEAST (1-180): 6.76e-67: 203: 75.56
+	Hs
		398248 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		398222 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Hs
		950543 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF1_HUMAN (1-181): 1.98e-68: 207: 96.13
+	Hs
		950686 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		574734 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89